{"id":"https://openalex.org/T13026","display_name":"Natural Compounds in Disease Treatment","description":"This cluster of papers explores the therapeutic potential of herbal medicines, focusing on compounds such as Celastrol and Triptolide derived from Thunder God Vine and Tripterygium wilfordii Hook F. The research covers their applications in treating inflammatory disorders, cancer, and neurodegenerative diseases, as well as their potential in targeting specific pathways like NF-?B, inducing apoptosis, and acting as antioxidants. Additionally, the cluster delves into the use of these herbal medicines in conditions like rheumatoid arthritis through drug targeting approaches.","keywords":[{"id":"https://openalex.org/keywords/triptolide","display_name":"triptolide","score":0.5168},{"id":"https://openalex.org/keywords/tripterygium-wilfordii","display_name":"Tripterygium wilfordii","score":0.453},{"id":"https://openalex.org/keywords/anti-arthritic-activity","display_name":"anti-arthritic activity","score":0.2545},{"id":"https://openalex.org/keywords/celastrol","display_name":"celastrol","score":0.2853},{"id":"https://openalex.org/keywords/complete-freund-s-adjuvant-induced-arthritis","display_name":"complete Freund's adjuvant-induced arthritis","score":0.3075},{"id":"https://openalex.org/keywords/tripterygium-glycosides","display_name":"tripterygium glycosides","score":0.2788},{"id":"https://openalex.org/keywords/tripterygium-hypoglaucum","display_name":"Tripterygium hypoglaucum","score":0.358},{"id":"https://openalex.org/keywords/tripterygium","display_name":"Tripterygium","score":0.303},{"id":"https://openalex.org/keywords/paw-volume","display_name":"paw volume","score":0.2132},{"id":"https://openalex.org/keywords/triptonide","display_name":"triptonide","score":0.3561},{"id":"https://openalex.org/keywords/formaldehyde-induced-arthritis","display_name":"formaldehyde-induced arthritis","score":0.2807},{"id":"https://openalex.org/keywords/mh7a-cells","display_name":"MH7A cells","score":0.2751},{"id":"https://openalex.org/keywords/tripterygium-wilfordii-glycosides","display_name":"Tripterygium wilfordii glycosides","score":0.2687},{"id":"https://openalex.org/keywords/minnelide","display_name":"Minnelide","score":0.2723},{"id":"https://openalex.org/keywords/tripterygium-wilfordii-polysaccharide","display_name":"Tripterygium wilfordii polysaccharide","score":0.3602},{"id":"https://openalex.org/keywords/tripterygium-wilfordii-polyglycoside","display_name":"Tripterygium wilfordii polyglycoside","score":0.238},{"id":"https://openalex.org/keywords/arthritis-index","display_name":"arthritis index","score":0.3055},{"id":"https://openalex.org/keywords/xinfeng-capsule","display_name":"Xinfeng capsule","score":0.2093},{"id":"https://openalex.org/keywords/cfa-induced-arthritis","display_name":"CFA-induced arthritis","score":0.2228},{"id":"https://openalex.org/keywords/demethylzeylasteral","display_name":"demethylzeylasteral","score":0.2683},{"id":"https://openalex.org/keywords/knee-joint-histopathology","display_name":"knee joint histopathology","score":0.2563}],"legacy_keywords":"Celastrol; Triptolide; Traditional Medicines; Inflammatory Disorders; Cancer Treatment; NF-?B Inhibition; Apoptosis Induction; Antioxidant Activity; Rheumatoid Arthritis; Drug Targeting","ids":{"openalex":"https://openalex.org/T13026","wikipedia":"https://en.wikipedia.org/wiki/Traditional_Chinese_medicine"},"subfield":{"id":"https://openalex.org/subfields/2707","display_name":"Complementary and alternative medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"},"siblings":[{"id":"https://openalex.org/T10902","display_name":"Complementary and Alternative Medicine Studies"},{"id":"https://openalex.org/T11209","display_name":"Cardiovascular and exercise physiology"},{"id":"https://openalex.org/T11327","display_name":"Acupuncture Treatment Research Studies"},{"id":"https://openalex.org/T11709","display_name":"Traditional Chinese Medicine Analysis"},{"id":"https://openalex.org/T12298","display_name":"Phytochemicals and Medicinal Plants"},{"id":"https://openalex.org/T12647","display_name":"Traditional Chinese Medicine Studies"},{"id":"https://openalex.org/T12750","display_name":"Nigella sativa pharmacological applications"},{"id":"https://openalex.org/T12846","display_name":"Ginkgo biloba and Cashew Applications"},{"id":"https://openalex.org/T12891","display_name":"Medicinal Plants and Neuroprotection"},{"id":"https://openalex.org/T13090","display_name":"Medicinal Plant Extracts Effects"},{"id":"https://openalex.org/T13281","display_name":"Andrographolide Research and Applications"},{"id":"https://openalex.org/T13444","display_name":"Medical Research and Treatments"},{"id":"https://openalex.org/T13483","display_name":"Herbal Medicine Research Studies"},{"id":"https://openalex.org/T13776","display_name":"Phytochemical and Pharmacological Studies"},{"id":"https://openalex.org/T13792","display_name":"Morinda citrifolia extract uses"},{"id":"https://openalex.org/T13846","display_name":"Mangiferin and Mango Extracts"},{"id":"https://openalex.org/T13919","display_name":"Medicinal plant effects and applications"},{"id":"https://openalex.org/T14461","display_name":"Medicinal Plant Studies"},{"id":"https://openalex.org/T14478","display_name":"Papaya Research and Applications"}],"works_count":13305,"cited_by_count":192847,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T13026","updated_date":"2026-10-22T03:01:35","created_date":"2024-01-23T15:27:16"}