{"id":"https://openalex.org/T12748","display_name":"Molecular spectroscopy and chirality","description":"This cluster of papers focuses on the application of chiroptical spectroscopic methods, such as vibrational circular dichroism and optical rotation, combined with computational techniques like density functional theory and NMR, for the determination of absolute configuration, conformational analysis, and stereochemistry in organic compounds, particularly natural products. The cluster also explores the role of chiroptical spectroscopy in structure elucidation and its use in studying the chiral properties of molecules.","keywords":[{"id":"https://openalex.org/keywords/optical-activity","display_name":"optical activity","score":0.2363},{"id":"https://openalex.org/keywords/chiral-molecules","display_name":"chiral molecules","score":0.2428},{"id":"https://openalex.org/keywords/optical-rotation","display_name":"optical rotation","score":0.2416},{"id":"https://openalex.org/keywords/vibrational-circular-dichroism","display_name":"vibrational circular dichroism","score":0.6018},{"id":"https://openalex.org/keywords/optical-rotatory-dispersion","display_name":"optical rotatory dispersion","score":0.4188},{"id":"https://openalex.org/keywords/chiroptical-properties","display_name":"chiroptical properties","score":0.2509},{"id":"https://openalex.org/keywords/cotton-effect","display_name":"Cotton effect","score":0.4709},{"id":"https://openalex.org/keywords/raman-optical-activity","display_name":"Raman optical activity","score":0.4928},{"id":"https://openalex.org/keywords/configurational-assignment","display_name":"configuration assignment","score":0.2414},{"id":"https://openalex.org/keywords/stereochemical-assignment","display_name":"stereochemical assignment","score":0.2504},{"id":"https://openalex.org/keywords/chiroptical-spectroscopy","display_name":"chiroptical spectroscopy","score":0.5688},{"id":"https://openalex.org/keywords/natural-product-stereochemistry","display_name":"natural product stereochemistry","score":0.382},{"id":"https://openalex.org/keywords/vicinal-coupling-constants","display_name":"vicinal coupling constants","score":0.3006},{"id":"https://openalex.org/keywords/rotatory-strength","display_name":"rotational strength","score":0.5004},{"id":"https://openalex.org/keywords/chiral-shift-reagents","display_name":"chiral shift reagents","score":0.5667},{"id":"https://openalex.org/keywords/chiral-solvating-agents","display_name":"chiral solvating agents","score":0.5665},{"id":"https://openalex.org/keywords/configuration-determination","display_name":"configuration determination","score":0.2309},{"id":"https://openalex.org/keywords/absolute-configuration-determination","display_name":"absolute configuration determination","score":0.3808},{"id":"https://openalex.org/keywords/enantiomeric-excess-determination","display_name":"enantiomeric excess determination","score":0.3242},{"id":"https://openalex.org/keywords/chiral-solvents","display_name":"chiral solvents","score":0.3304},{"id":"https://openalex.org/keywords/lanthanide-shift-reagents","display_name":"lanthanide shift reagents","score":0.2519},{"id":"https://openalex.org/keywords/stereochemistry-determination","display_name":"stereochemistry determination","score":0.3639},{"id":"https://openalex.org/keywords/exciton-chirality","display_name":"exciton chirality","score":0.4555},{"id":"https://openalex.org/keywords/vibrational-optical-activity","display_name":"vibrational optical activity","score":0.7744},{"id":"https://openalex.org/keywords/lanthanide-induced-shifts","display_name":"lanthanide-induced shifts","score":0.3121}],"legacy_keywords":"Chiroptical Spectroscopy; Absolute Configuration; NMR; Density Functional Theory; Vibrational Circular Dichroism; Optical Rotation; Conformational Analysis; Natural Products; Structure Elucidation; Stereochemistry","ids":{"openalex":"https://openalex.org/T12748","wikipedia":"https://en.wikipedia.org/wiki/Chiroptical_spectroscopy"},"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"},"siblings":[{"id":"https://openalex.org/T10519","display_name":"Advanced Proteomics Techniques and Applications"},{"id":"https://openalex.org/T10532","display_name":"Molecular Sensors and Ion Detection"},{"id":"https://openalex.org/T10683","display_name":"Mass Spectrometry Techniques and Applications"},{"id":"https://openalex.org/T10908","display_name":"Analytical Chemistry and Chromatography"},{"id":"https://openalex.org/T11111","display_name":"Spectroscopy and Laser Applications"},{"id":"https://openalex.org/T11809","display_name":"Advanced NMR Techniques and Applications"},{"id":"https://openalex.org/T12195","display_name":"Aerogels and thermal insulation"},{"id":"https://openalex.org/T12967","display_name":"Molecular Spectroscopy and Structure"},{"id":"https://openalex.org/T13604","display_name":"Adsorption, diffusion, and thermodynamic properties of materials"},{"id":"https://openalex.org/T13675","display_name":"Diffusion Coefficients in Liquids"},{"id":"https://openalex.org/T14068","display_name":"Organic and Inorganic Chemical Reactions"}],"works_count":47602,"cited_by_count":567444,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T12748","updated_date":"2026-10-21T03:01:35","created_date":"2024-01-23T15:27:15"}