{"id":"https://openalex.org/T12494","display_name":"Alcoholism and Thiamine Deficiency","description":"This cluster of papers focuses on the diagnosis and management of Wernicke-Korsakoff Syndrome, a neurological disorder primarily caused by thiamine deficiency, often associated with alcohol misuse. The papers cover topics such as neuropathology, alcohol withdrawal, diabetic complications, benzodiazepine therapy, neuroimaging, alcoholic neuropathy, and the role of oxidative stress and vitamin B1 in the syndrome.","keywords":[{"id":"https://openalex.org/keywords/thiamine-deficiency","display_name":"thiamine deficiency","score":0.7173},{"id":"https://openalex.org/keywords/thiamine","display_name":"thiamine","score":0.2568},{"id":"https://openalex.org/keywords/alcohol-withdrawal-syndrome","display_name":"alcohol withdrawal","score":0.3641},{"id":"https://openalex.org/keywords/wernicke-encephalopathy","display_name":"Wernicke's encephalopathy","score":0.8049},{"id":"https://openalex.org/keywords/delirium-tremens","display_name":"delirium tremens","score":0.6597},{"id":"https://openalex.org/keywords/beriberi","display_name":"beriberi","score":0.6537},{"id":"https://openalex.org/keywords/korsakoff-syndrome","display_name":"Korsakoff syndrome","score":0.614},{"id":"https://openalex.org/keywords/thiamine-supplementation","display_name":"thiamine supplementation","score":0.6293},{"id":"https://openalex.org/keywords/thiamine-metabolism","display_name":"thiamine metabolism","score":0.4734},{"id":"https://openalex.org/keywords/wernicke-korsakoff-syndrome","display_name":"Wernicke-Korsakoff syndrome","score":0.8163},{"id":"https://openalex.org/keywords/thiamine-derivatives","display_name":"thiamine derivatives","score":0.4862},{"id":"https://openalex.org/keywords/thiamine-therapy","display_name":"thiamine therapy","score":0.651},{"id":"https://openalex.org/keywords/marchiafava-bignami-disease","display_name":"Marchiafava-Bignami disease","score":0.7752},{"id":"https://openalex.org/keywords/alcohol-related-brain-damage","display_name":"alcohol-related brain damage","score":0.6293},{"id":"https://openalex.org/keywords/alcoholic-neuropathy","display_name":"alcoholic neuropathy","score":0.5751},{"id":"https://openalex.org/keywords/ciwa-ar","display_name":"CIWA-Ar","score":0.769},{"id":"https://openalex.org/keywords/alcohol-withdrawal-treatment","display_name":"alcohol withdrawal treatment","score":0.4839},{"id":"https://openalex.org/keywords/alcohol-related-dementia","display_name":"alcohol-related dementia","score":0.5159},{"id":"https://openalex.org/keywords/pyrithiamine","display_name":"pyrithiamine","score":0.6242},{"id":"https://openalex.org/keywords/thiamine-uptake","display_name":"thiamine uptake","score":0.5477},{"id":"https://openalex.org/keywords/alcohol-related-neurological-disorders","display_name":"alcohol-related neurological disorders","score":0.8259},{"id":"https://openalex.org/keywords/thiamine-disulfide","display_name":"thiamine disulfide","score":0.5393},{"id":"https://openalex.org/keywords/alcohol-withdrawal-seizures","display_name":"alcohol withdrawal seizures","score":0.4859},{"id":"https://openalex.org/keywords/alcohol-induced-psychosis","display_name":"alcohol-induced psychosis","score":0.4851},{"id":"https://openalex.org/keywords/intravenous-thiamine","display_name":"intravenous thiamine","score":0.8867}],"legacy_keywords":"Wernicke-Korsakoff Syndrome; Thiamine Deficiency; Alcohol Withdrawal; Neuropathology; Diabetic Complications; Benzodiazepine Therapy; Neuroimaging; Alcoholic Neuropathy; Oxidative Stress; Vitamin B1","ids":{"openalex":"https://openalex.org/T12494","wikipedia":"https://en.wikipedia.org/wiki/Wernicke%E2%80%93Korsakoff_syndrome"},"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"},"siblings":[{"id":"https://openalex.org/T10085","display_name":"Parkinson's Disease Mechanisms and Treatments"},{"id":"https://openalex.org/T10420","display_name":"Intracranial Aneurysms: Treatment and Complications"},{"id":"https://openalex.org/T10706","display_name":"Traumatic Brain Injury and Neurovascular Disturbances"},{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research"},{"id":"https://openalex.org/T10919","display_name":"Neurological disorders and treatments"},{"id":"https://openalex.org/T11173","display_name":"Neurofibromatosis and Schwannoma Cases"},{"id":"https://openalex.org/T11271","display_name":"Myasthenia Gravis and Thymoma"},{"id":"https://openalex.org/T11274","display_name":"Botulinum Toxin and Related Neurological Disorders"},{"id":"https://openalex.org/T11368","display_name":"Long-Term Effects of COVID-19"},{"id":"https://openalex.org/T11402","display_name":"Vascular Malformations Diagnosis and Treatment"},{"id":"https://openalex.org/T11627","display_name":"Autoimmune Neurological Disorders and Treatments"},{"id":"https://openalex.org/T11735","display_name":"Peripheral Neuropathies and Disorders"},{"id":"https://openalex.org/T11763","display_name":"Intracerebral and Subarachnoid Hemorrhage Research"},{"id":"https://openalex.org/T11929","display_name":"Cerebral Venous Sinus Thrombosis"},{"id":"https://openalex.org/T12212","display_name":"CNS Lymphoma Diagnosis and Treatment"},{"id":"https://openalex.org/T12226","display_name":"Neuroblastoma Research and Treatments"},{"id":"https://openalex.org/T12301","display_name":"Facial Nerve Paralysis Treatment and Research"},{"id":"https://openalex.org/T12622","display_name":"Neurosurgical Procedures and Complications"},{"id":"https://openalex.org/T13648","display_name":"Cerebrovascular and genetic disorders"},{"id":"https://openalex.org/T13735","display_name":"History of Medical Practice"},{"id":"https://openalex.org/T14286","display_name":"Parkinson's Disease and Spinal Disorders"}],"works_count":34311,"cited_by_count":302760,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T12494","updated_date":"2026-10-20T03:01:21","created_date":"2024-01-23T15:27:14"}