{"id":"https://openalex.org/T12286","display_name":"Erythrocyte Function and Pathophysiology","description":"This cluster of papers focuses on the role of mechanosensitive ion channels, particularly Piezo1 and Piezo2, in various physiological processes such as mechanotransduction, erythrocyte function, sensory neuron response, and erythropoiesis. It also explores the implications of these channels in diseases related to erythrocytes, sensory perception, and cellular mechanosensation.","keywords":[{"id":"https://openalex.org/keywords/erythrocyte-membrane","display_name":"erythrocyte membrane","score":0.2757},{"id":"https://openalex.org/keywords/hereditary-spherocytosis","display_name":"hereditary spherocytosis","score":0.3595},{"id":"https://openalex.org/keywords/spectrin","display_name":"spectrin","score":0.2936},{"id":"https://openalex.org/keywords/erythrocyte-metabolism","display_name":"erythrocyte metabolism","score":0.3119},{"id":"https://openalex.org/keywords/band-3","display_name":"band 3","score":0.2973},{"id":"https://openalex.org/keywords/erythrocyte-ghosts","display_name":"erythrocyte ghosts","score":0.2164},{"id":"https://openalex.org/keywords/osmotic-fragility","display_name":"osmotic fragility","score":0.3},{"id":"https://openalex.org/keywords/erythrocyte-membrane-proteins","display_name":"erythrocyte membrane proteins","score":0.3577},{"id":"https://openalex.org/keywords/hereditary-elliptocytosis","display_name":"hereditary elliptocytosis","score":0.5143},{"id":"https://openalex.org/keywords/eryptosis","display_name":"eryptosis","score":0.5233},{"id":"https://openalex.org/keywords/erythrocyte-aging","display_name":"erythrocyte aging","score":0.4901},{"id":"https://openalex.org/keywords/red-cell-membrane-disorders","display_name":"red blood cell membrane disorders","score":0.3785},{"id":"https://openalex.org/keywords/ankyrin","display_name":"ankyrin","score":0.3706},{"id":"https://openalex.org/keywords/erythrocyte-osmotic-fragility","display_name":"erythrocyte osmotic fragility","score":0.2704},{"id":"https://openalex.org/keywords/erythrocyte-lifespan","display_name":"erythrocyte lifespan","score":0.3287},{"id":"https://openalex.org/keywords/band-3-protein","display_name":"band 3 protein","score":0.3572},{"id":"https://openalex.org/keywords/erythrocyte-cytoskeleton","display_name":"erythrocyte cytoskeleton","score":0.4617},{"id":"https://openalex.org/keywords/erythrocyte-membrane-permeability","display_name":"erythrocyte membrane permeability","score":0.3494},{"id":"https://openalex.org/keywords/membrane-skeleton","display_name":"membrane skeleton","score":0.2534},{"id":"https://openalex.org/keywords/erythrocyte-membrane-skeleton","display_name":"erythrocyte membrane skeleton","score":0.6418},{"id":"https://openalex.org/keywords/spherocytes","display_name":"spherocytes","score":0.3255},{"id":"https://openalex.org/keywords/protein-4-1","display_name":"protein 4.1","score":0.4614},{"id":"https://openalex.org/keywords/echinocytes","display_name":"echinocytes","score":0.2343},{"id":"https://openalex.org/keywords/erythrocyte-shape","display_name":"erythrocyte shape","score":0.3818},{"id":"https://openalex.org/keywords/osmotic-resistance","display_name":"osmotic resistance","score":0.2698}],"legacy_keywords":"Piezo1; Piezo2; mechanotransduction; erythrocyte; mechanosensation; ion channels; membrane; sensory neurons; erythropoiesis; apoptosis","ids":{"openalex":"https://openalex.org/T12286","wikipedia":"https://en.wikipedia.org/wiki/Mechanosensitive_ion_channel"},"subfield":{"id":"https://openalex.org/subfields/2737","display_name":"Physiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"},"siblings":[{"id":"https://openalex.org/T10051","display_name":"Asthma and respiratory diseases"},{"id":"https://openalex.org/T10060","display_name":"Smoking Behavior and Cessation"},{"id":"https://openalex.org/T10086","display_name":"Alzheimer's disease research and treatments"},{"id":"https://openalex.org/T10155","display_name":"Nitric Oxide and Endothelin Effects"},{"id":"https://openalex.org/T10196","display_name":"Pain Mechanisms and Treatments"},{"id":"https://openalex.org/T10234","display_name":"Obstructive Sleep Apnea Research"},{"id":"https://openalex.org/T10352","display_name":"Physical Activity and Health"},{"id":"https://openalex.org/T10397","display_name":"Nutrition and Health in Aging"},{"id":"https://openalex.org/T10863","display_name":"Voice and Speech Disorders"},{"id":"https://openalex.org/T10937","display_name":"Telomeres, Telomerase, and Senescence"},{"id":"https://openalex.org/T10945","display_name":"Lysosomal Storage Disorders Research"},{"id":"https://openalex.org/T11109","display_name":"Thermoregulation and physiological responses"},{"id":"https://openalex.org/T11238","display_name":"Simulation-Based Education in Healthcare"},{"id":"https://openalex.org/T11314","display_name":"Clinical Laboratory Practices and Quality Control"},{"id":"https://openalex.org/T11457","display_name":"Adipose Tissue and Metabolism"},{"id":"https://openalex.org/T11521","display_name":"Salivary Gland Disorders and Functions"},{"id":"https://openalex.org/T11571","display_name":"Sarcoidosis and Beryllium Toxicity Research"},{"id":"https://openalex.org/T11909","display_name":"Histiocytic Disorders and Treatments"},{"id":"https://openalex.org/T11934","display_name":"Syphilis Diagnosis and Treatment"},{"id":"https://openalex.org/T12005","display_name":"Spaceflight effects on biology"},{"id":"https://openalex.org/T12049","display_name":"Tuberous Sclerosis Complex Research"},{"id":"https://openalex.org/T12267","display_name":"Diet and metabolism studies"},{"id":"https://openalex.org/T12279","display_name":"Body Composition Measurement Techniques"},{"id":"https://openalex.org/T12625","display_name":"Sympathectomy and Hyperhidrosis Treatments"},{"id":"https://openalex.org/T12745","display_name":"Dietary Effects on Health"},{"id":"https://openalex.org/T13044","display_name":"Biofield Effects and Biophysics"},{"id":"https://openalex.org/T13417","display_name":"Biomedical Ethics and Regulation"},{"id":"https://openalex.org/T13551","display_name":"Biochemical effects in animals"},{"id":"https://openalex.org/T14344","display_name":"Pathogenesis and Treatment of Hiccups"}],"works_count":27075,"cited_by_count":429067,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T12286","updated_date":"2026-10-18T03:01:31","created_date":"2024-01-23T15:27:13"}