{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","description":"This cluster of papers focuses on the epidemiology, pathogenesis, clinical manifestations, treatment, and prevention of Human T-cell Leukemia Virus Type 1 (HTLV-1) infection. It covers topics such as viral transmission, proviral load, cellular transformation, immunotherapy, and the role of viral oncogenes in leukemia and lymphoma development.","keywords":[{"id":"https://openalex.org/keywords/htlv-1","display_name":"HTLV-1","score":0.784},{"id":"https://openalex.org/keywords/adult-t-cell-leukemia-lymphoma","display_name":"adult T-cell leukemia/lymphoma","score":0.7885},{"id":"https://openalex.org/keywords/bovine-leukemia-virus","display_name":"bovine leukemia virus","score":0.7793},{"id":"https://openalex.org/keywords/retroviruses","display_name":"retroviruses","score":0.2514},{"id":"https://openalex.org/keywords/htlv-1-associated-myelopathy","display_name":"tropical spastic paraparesis","score":0.8046},{"id":"https://openalex.org/keywords/htlv-2","display_name":"HTLV-II","score":0.8435},{"id":"https://openalex.org/keywords/bovine-leukosis","display_name":"bovine leukosis","score":0.657},{"id":"https://openalex.org/keywords/murine-leukemia-virus","display_name":"murine leukemia virus","score":0.5003},{"id":"https://openalex.org/keywords/rous-sarcoma-virus","display_name":"Rous sarcoma virus","score":0.408},{"id":"https://openalex.org/keywords/htlv","display_name":"HTLV","score":0.615},{"id":"https://openalex.org/keywords/htlv-1-infection","display_name":"HTLV-1 infection","score":0.7147},{"id":"https://openalex.org/keywords/long-terminal-repeat","display_name":"long terminal repeat","score":0.2183},{"id":"https://openalex.org/keywords/ham-tsp","display_name":"HAM/TSP","score":0.8422},{"id":"https://openalex.org/keywords/feline-leukemia-virus","display_name":"feline leukemia virus","score":0.2601},{"id":"https://openalex.org/keywords/moloney-murine-leukemia-virus","display_name":"Moloney murine leukemia virus","score":0.4134},{"id":"https://openalex.org/keywords/proviral-load","display_name":"proviral load","score":0.7921},{"id":"https://openalex.org/keywords/tax-protein","display_name":"Tax protein","score":0.8499},{"id":"https://openalex.org/keywords/retrovirus-infection","display_name":"retroviral infection","score":0.2692},{"id":"https://openalex.org/keywords/retroviral-oncogenesis","display_name":"retroviral oncogenesis","score":0.5823},{"id":"https://openalex.org/keywords/t-cell-leukemia","display_name":"T-cell leukemia","score":0.2517},{"id":"https://openalex.org/keywords/mouse-mammary-tumor-virus","display_name":"mouse mammary tumor virus","score":0.271},{"id":"https://openalex.org/keywords/env-gene","display_name":"env gene","score":0.2108},{"id":"https://openalex.org/keywords/proviral-dna","display_name":"proviral DNA","score":0.283},{"id":"https://openalex.org/keywords/retroviral-oncogenes","display_name":"retroviral oncogenes","score":0.4413},{"id":"https://openalex.org/keywords/htlv-1-associated-myelopathy-tropical-spastic-paraparesis","display_name":"HTLV-1-associated myelopathy/tropical spastic paraparesis","score":0.9189}],"legacy_keywords":"HTLV-1; infection; leukemia; lymphoma; viral transmission; proviral load; cellular transformation; epidemiology; immunotherapy; viral oncogenes","ids":{"openalex":"https://openalex.org/T12159","wikipedia":"https://en.wikipedia.org/wiki/Human_T-cell_leukemia_virus_type_1"},"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"},"siblings":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology"},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation"},{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis"},{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota"},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses"},{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases"},{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction"},{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer"},{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine"},{"id":"https://openalex.org/T11403","display_name":"Invertebrate Immune Response Mechanisms"},{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy"},{"id":"https://openalex.org/T11597","display_name":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms"},{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses"},{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders"},{"id":"https://openalex.org/T12255","display_name":"Biosimilars and Bioanalytical Methods"},{"id":"https://openalex.org/T12387","display_name":"Galectins and Cancer Biology"},{"id":"https://openalex.org/T12477","display_name":"Toxin Mechanisms and Immunotoxins"},{"id":"https://openalex.org/T12528","display_name":"IL-33, ST2, and ILC Pathways"},{"id":"https://openalex.org/T12672","display_name":"Phagocytosis and Immune Regulation"},{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases"},{"id":"https://openalex.org/T13254","display_name":"Macrophage Migration Inhibitory Factor"},{"id":"https://openalex.org/T13410","display_name":"Immune responses and vaccinations"},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses"},{"id":"https://openalex.org/T14165","display_name":"Inflammation biomarkers and pathways"},{"id":"https://openalex.org/T14245","display_name":"Biomarkers in Disease Mechanisms"}],"works_count":50811,"cited_by_count":976716,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T12159","updated_date":"2026-10-20T03:01:21","created_date":"2024-01-23T15:27:13"}