{"id":"https://openalex.org/T12059","display_name":"Berberine and alkaloids research","description":"This cluster of papers focuses on the therapeutic potential of berberine alkaloids, particularly in the context of metabolic disorders such as diabetes mellitus. The research covers various aspects including the mechanisms of action, anti-inflammatory effects, cholesterol-lowering properties, and potential anticancer activities. Additionally, it explores the traditional use of berberine in Chinese medicine and its impact on glucose metabolism.","keywords":[{"id":"https://openalex.org/keywords/berberine","display_name":"berberine","score":0.3357},{"id":"https://openalex.org/keywords/protoberberine-alkaloids","display_name":"protoberberine alkaloids","score":0.3174},{"id":"https://openalex.org/keywords/berberine-derivatives","display_name":"berberine derivatives","score":0.5505},{"id":"https://openalex.org/keywords/berberine-alkaloids","display_name":"berberine alkaloids","score":0.4069},{"id":"https://openalex.org/keywords/berbamine","display_name":"berbamine","score":0.2715},{"id":"https://openalex.org/keywords/berberine-chloride","display_name":"berberine chloride","score":0.2499},{"id":"https://openalex.org/keywords/berberrubine","display_name":"berberrubine","score":0.4437},{"id":"https://openalex.org/keywords/tetrahydroberberine","display_name":"tetrahydroberberine","score":0.3893},{"id":"https://openalex.org/keywords/dihydroberberine","display_name":"dihydroberberine","score":0.5481},{"id":"https://openalex.org/keywords/tetrahydroprotoberberines","display_name":"tetrahydroprotoberberines","score":0.26},{"id":"https://openalex.org/keywords/columbamine","display_name":"columbamine","score":0.2026},{"id":"https://openalex.org/keywords/protoberberines","display_name":"protoberberines","score":0.2286},{"id":"https://openalex.org/keywords/tetrahydroprotoberberine-alkaloids","display_name":"tetrahydroprotoberberine alkaloids","score":0.2664},{"id":"https://openalex.org/keywords/berberine-sulfate","display_name":"berberine sulfate","score":0.2267}],"legacy_keywords":"Berberine; Alkaloids; Metabolic Effects; Diabetes Mellitus; Anti-inflammatory; AMP-Activated Protein Kinase; Cholesterol-lowering; Anticancer; Glucose Metabolism; Traditional Medicine","ids":{"openalex":"https://openalex.org/T12059","wikipedia":"https://en.wikipedia.org/wiki/Berberine"},"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"},"siblings":[{"id":"https://openalex.org/T10084","display_name":"Musculoskeletal pain and rehabilitation"},{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis"},{"id":"https://openalex.org/T10414","display_name":"Cannabis and Cannabinoid Research"},{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects"},{"id":"https://openalex.org/T11036","display_name":"Antibiotics Pharmacokinetics and Efficacy"},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression"},{"id":"https://openalex.org/T11085","display_name":"Fungal Biology and Applications"},{"id":"https://openalex.org/T11117","display_name":"Drug-Induced Adverse Reactions"},{"id":"https://openalex.org/T11264","display_name":"Coffee research and impacts"},{"id":"https://openalex.org/T12023","display_name":"Cholinesterase and Neurodegenerative Diseases"},{"id":"https://openalex.org/T12539","display_name":"Pharmacology and Obesity Treatment"},{"id":"https://openalex.org/T12582","display_name":"Flavonoids in Medical Research"},{"id":"https://openalex.org/T13023","display_name":"Synthesis of Organic Compounds"},{"id":"https://openalex.org/T13130","display_name":"Biological and pharmacological studies of plants"},{"id":"https://openalex.org/T13335","display_name":"Pharmacological Effects of Medicinal Plants"},{"id":"https://openalex.org/T13365","display_name":"Medical and Biological Ozone Research"},{"id":"https://openalex.org/T13505","display_name":"Apelin-related biomedical research"},{"id":"https://openalex.org/T13767","display_name":"Leech Biology and Applications"},{"id":"https://openalex.org/T13809","display_name":"Philosophy, Health, and Society"},{"id":"https://openalex.org/T13921","display_name":"Biological Stains and Phytochemicals"},{"id":"https://openalex.org/T14028","display_name":"Healthcare and Venom Research"}],"works_count":9998,"cited_by_count":194660,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T12059","updated_date":"2026-10-21T03:01:35","created_date":"2024-01-23T15:27:12"}