{"id":"https://openalex.org/T11752","display_name":"Cancer Treatment and Pharmacology","description":"This cluster of papers focuses on the chemotherapy-induced peripheral neuropathy (CIPN) experienced by cancer patients, particularly in the context of breast cancer treatment. It covers various aspects such as the neurotoxic effects of taxanes and oxaliplatin, neuroprotective strategies, and the impact of CIPN on the quality of life of patients. Additionally, it discusses the use of microtubule-targeting agents like Eribulin Mesylate in cancer treatment.","keywords":[{"id":"https://openalex.org/keywords/chemotherapy-induced-peripheral-neuropathy","display_name":"chemotherapy-induced peripheral neuropathy","score":0.7192},{"id":"https://openalex.org/keywords/chemotherapy-induced-neurotoxicity","display_name":"chemotherapy-induced neurotoxicity","score":0.3936},{"id":"https://openalex.org/keywords/eribulin","display_name":"eribulin","score":0.3085},{"id":"https://openalex.org/keywords/neuropathy-prevention","display_name":"neuropathy prevention","score":0.6595},{"id":"https://openalex.org/keywords/taxane-resistance","display_name":"taxane resistance","score":0.2345},{"id":"https://openalex.org/keywords/anthracycline-resistance","display_name":"anthracycline resistance","score":0.241},{"id":"https://openalex.org/keywords/ixabepilone","display_name":"ixabepilone","score":0.4588},{"id":"https://openalex.org/keywords/drug-induced-neuropathy","display_name":"drug-induced neuropathy","score":0.2186},{"id":"https://openalex.org/keywords/oxaliplatin-induced-peripheral-neuropathy","display_name":"oxaliplatin-induced peripheral neuropathy","score":0.5587},{"id":"https://openalex.org/keywords/paclitaxel-induced-peripheral-neuropathy","display_name":"paclitaxel-induced peripheral neuropathy","score":0.596},{"id":"https://openalex.org/keywords/peripheral-neurotoxicity","display_name":"peripheral neurotoxicity","score":0.4644},{"id":"https://openalex.org/keywords/epothilones","display_name":"epothilones","score":0.2537},{"id":"https://openalex.org/keywords/eribulin-mesylate","display_name":"eribulin mesylate","score":0.56},{"id":"https://openalex.org/keywords/peripheral-sensory-neuropathy","display_name":"peripheral sensory neuropathy","score":0.2031},{"id":"https://openalex.org/keywords/neurotoxic-chemotherapy","display_name":"neurotoxic chemotherapy","score":0.7968},{"id":"https://openalex.org/keywords/anthracycline-pretreated-patients","display_name":"anthracycline-pretreated patients","score":0.653},{"id":"https://openalex.org/keywords/anthracycline-refractory-disease","display_name":"anthracycline-refractory disease","score":0.5174},{"id":"https://openalex.org/keywords/taxane-induced-peripheral-neuropathy","display_name":"taxane-induced peripheral neuropathy","score":0.8883},{"id":"https://openalex.org/keywords/drug-induced-peripheral-neuropathy","display_name":"drug-induced peripheral neuropathy","score":0.4089},{"id":"https://openalex.org/keywords/neuropathy-severity","display_name":"neuropathy severity","score":0.2427},{"id":"https://openalex.org/keywords/eortc-qlq-cipn20","display_name":"EORTC QLQ-CIPN20","score":0.9432},{"id":"https://openalex.org/keywords/chemotherapy-induced-neuropathic-pain","display_name":"chemotherapy-induced neuropathic pain","score":0.3},{"id":"https://openalex.org/keywords/taxane-refractory-disease","display_name":"taxane-refractory disease","score":0.4615},{"id":"https://openalex.org/keywords/neuropathy-treatment","display_name":"neuropathy treatment","score":0.2163},{"id":"https://openalex.org/keywords/total-neuropathy-score","display_name":"Total Neuropathy Score","score":0.6238}],"legacy_keywords":"Chemotherapy-Induced Peripheral Neuropathy; Taxanes; Oxaliplatin; Paclitaxel; Neurotoxicity; Metastatic Breast Cancer; Eribulin Mesylate; Neuroprotective Strategies; Microtubule-Targeting Agents; Quality of Life","ids":{"openalex":"https://openalex.org/T11752","wikipedia":"https://en.wikipedia.org/wiki/Chemotherapy-induced_peripheral_neuropathy"},"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"},"siblings":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers"},{"id":"https://openalex.org/T10163","display_name":"Metal complexes synthesis and properties"},{"id":"https://openalex.org/T10178","display_name":"Cancer survivorship and care"},{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research"},{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments"},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis"},{"id":"https://openalex.org/T10392","display_name":"Cutaneous Melanoma Detection and Management"},{"id":"https://openalex.org/T10552","display_name":"Colorectal Cancer Screening and Detection"},{"id":"https://openalex.org/T10556","display_name":"Global Cancer Incidence and Screening"},{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms"},{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways"},{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders"},{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research"},{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies"},{"id":"https://openalex.org/T11221","display_name":"Bone health and treatments"},{"id":"https://openalex.org/T11296","display_name":"COVID-19 and healthcare impacts"},{"id":"https://openalex.org/T11355","display_name":"Inflammatory Biomarkers in Disease Prognosis"},{"id":"https://openalex.org/T11469","display_name":"Lymphatic System and Diseases"},{"id":"https://openalex.org/T11491","display_name":"CAR-T cell therapy research"},{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions"},{"id":"https://openalex.org/T11532","display_name":"Chemokine receptors and signaling"},{"id":"https://openalex.org/T11827","display_name":"Polyomavirus and related diseases"},{"id":"https://openalex.org/T11914","display_name":"PARP inhibition in cancer therapy"},{"id":"https://openalex.org/T12103","display_name":"Cancer Risks and Factors"},{"id":"https://openalex.org/T12172","display_name":"Neutropenia and Cancer Infections"},{"id":"https://openalex.org/T12278","display_name":"Vascular Tumors and Angiosarcomas"},{"id":"https://openalex.org/T12334","display_name":"Lung Cancer Research Studies"},{"id":"https://openalex.org/T12379","display_name":"Cancer Diagnosis and Treatment"},{"id":"https://openalex.org/T12505","display_name":"Peptidase Inhibition and Analysis"},{"id":"https://openalex.org/T12758","display_name":"Saffron Plant Research Studies"},{"id":"https://openalex.org/T13434","display_name":"Cancer Research and Treatment"},{"id":"https://openalex.org/T14326","display_name":"Ear and Head Tumors"},{"id":"https://openalex.org/T14364","display_name":"Clusterin in disease pathology"}],"works_count":29175,"cited_by_count":417250,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T11752","updated_date":"2026-10-19T03:01:26","created_date":"2024-01-23T15:27:11"}
