{"id":"https://openalex.org/T11650","display_name":"Skin and Cellular Biology Research","description":"This cluster of papers explores the biology, pathology, and molecular mechanisms related to keratins, intermediate filaments, and associated disorders such as epidermolysis bullosa, Netherton syndrome, and ichthyoses. It covers topics including keratin expression in human tissues, mutations in genes encoding serine protease inhibitors, the role of vimentin in cell adhesion and migration, and the structure and functions of keratin proteins in various epithelia.","keywords":[{"id":"https://openalex.org/keywords/intermediate-filaments","display_name":"intermediate filaments","score":0.3877},{"id":"https://openalex.org/keywords/epidermolysis-bullosa","display_name":"epidermolysis bullosa","score":0.661},{"id":"https://openalex.org/keywords/desmosomes","display_name":"desmosomes","score":0.2276},{"id":"https://openalex.org/keywords/keratinocyte-differentiation","display_name":"keratinocyte differentiation","score":0.2274},{"id":"https://openalex.org/keywords/dystrophic-epidermolysis-bullosa","display_name":"dystrophic epidermolysis bullosa","score":0.7911},{"id":"https://openalex.org/keywords/epidermal-differentiation","display_name":"epidermal differentiation","score":0.2824},{"id":"https://openalex.org/keywords/recessive-dystrophic-epidermolysis-bullosa","display_name":"recessive dystrophic epidermolysis bullosa","score":0.717},{"id":"https://openalex.org/keywords/keratinization","display_name":"keratinization","score":0.2147},{"id":"https://openalex.org/keywords/blistering-skin-disease","display_name":"blistering skin disease","score":0.2428},{"id":"https://openalex.org/keywords/type-vii-collagen","display_name":"type VII collagen","score":0.5763},{"id":"https://openalex.org/keywords/genetic-skin-diseases","display_name":"hereditary skin disease","score":0.2804},{"id":"https://openalex.org/keywords/epidermolysis-bullosa-simplex","display_name":"epidermolysis bullosa simplex","score":0.8744},{"id":"https://openalex.org/keywords/junctional-epidermolysis-bullosa","display_name":"junctional epidermolysis bullosa","score":0.837},{"id":"https://openalex.org/keywords/skin-fragility","display_name":"skin fragility","score":0.4747},{"id":"https://openalex.org/keywords/ichthyosis","display_name":"ichthyosis","score":0.2487},{"id":"https://openalex.org/keywords/keratinization-disorders","display_name":"keratinization disorders","score":0.2639},{"id":"https://openalex.org/keywords/keratin-14","display_name":"keratin 14","score":0.2368},{"id":"https://openalex.org/keywords/col7a1","display_name":"COL7A1","score":0.7087},{"id":"https://openalex.org/keywords/hemidesmosomes","display_name":"hemidesmosomes","score":0.3025},{"id":"https://openalex.org/keywords/cornified-envelope","display_name":"cornified envelope","score":0.545},{"id":"https://openalex.org/keywords/skin-blistering","display_name":"skin blistering","score":0.3449},{"id":"https://openalex.org/keywords/keratin-intermediate-filaments","display_name":"keratin intermediate filaments","score":0.6787},{"id":"https://openalex.org/keywords/anchoring-fibrils","display_name":"anchoring fibrils","score":0.6367},{"id":"https://openalex.org/keywords/keratin-5","display_name":"keratin 5","score":0.2597},{"id":"https://openalex.org/keywords/desmoplakin","display_name":"desmoplakin","score":0.2956}],"legacy_keywords":"Keratins; Intermediate Filaments; Epidermolysis Bullosa; Vimentin; Netherton Syndrome; Desmin; Skin Disorders; Neurofilaments; Cornified Envelope; Cell Adhesion","ids":{"openalex":"https://openalex.org/T11650","wikipedia":"https://en.wikipedia.org/wiki/Keratin"},"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"},"siblings":[{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions"},{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics"},{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion"},{"id":"https://openalex.org/T10825","display_name":"Plant Pathogens and Fungal Diseases"},{"id":"https://openalex.org/T11131","display_name":"Proteoglycans and glycosaminoglycans research"},{"id":"https://openalex.org/T11144","display_name":"melanin and skin pigmentation"},{"id":"https://openalex.org/T11150","display_name":"Endoplasmic Reticulum Stress and Disease"},{"id":"https://openalex.org/T11399","display_name":"Muscle metabolism and nutrition"},{"id":"https://openalex.org/T11685","display_name":"Zebrafish Biomedical Research Applications"},{"id":"https://openalex.org/T12065","display_name":"Hippo pathway signaling and YAP/TAZ"},{"id":"https://openalex.org/T12094","display_name":"Hemoglobin structure and function"},{"id":"https://openalex.org/T12533","display_name":"Aldose Reductase and Taurine"},{"id":"https://openalex.org/T12712","display_name":"Myofascial pain diagnosis and treatment"},{"id":"https://openalex.org/T12793","display_name":"Caveolin-1 and cellular processes"},{"id":"https://openalex.org/T13127","display_name":"Biotin and Related Studies"},{"id":"https://openalex.org/T13637","display_name":"Calpain Protease Function and Regulation"}],"works_count":41038,"cited_by_count":932966,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T11650","updated_date":"2026-10-21T03:01:35","created_date":"2024-01-23T15:27:11"}