{"id":"https://openalex.org/T11628","display_name":"Myeloproliferative Neoplasms: Diagnosis and Treatment","description":"This cluster of papers focuses on the molecular pathogenesis, diagnosis, treatment, and prognosis of myeloproliferative disorders such as polycythemia vera, essential thrombocythemia, and myelofibrosis. It covers topics such as JAK2 and CALR mutations, prognostic scoring systems, ruxolitinib therapy, hematologic response, leukemic transformation, and stem cell transplantation.","keywords":[{"id":"https://openalex.org/keywords/myeloproliferative-neoplasms","display_name":"myeloproliferative neoplasms","score":0.5448},{"id":"https://openalex.org/keywords/polycythemia-vera","display_name":"polycythemia vera","score":0.7776},{"id":"https://openalex.org/keywords/essential-thrombocythemia","display_name":"essential thrombocythemia","score":0.7693},{"id":"https://openalex.org/keywords/myelofibrosis","display_name":"myelofibrosis","score":0.6679},{"id":"https://openalex.org/keywords/jak2-v617f-mutation","display_name":"JAK2 V617F mutation","score":0.8553},{"id":"https://openalex.org/keywords/primary-myelofibrosis","display_name":"primary myelofibrosis","score":0.8852},{"id":"https://openalex.org/keywords/ruxolitinib","display_name":"ruxolitinib","score":0.3912},{"id":"https://openalex.org/keywords/jak2-mutation","display_name":"JAK2 mutation","score":0.7487},{"id":"https://openalex.org/keywords/calr-mutation","display_name":"CALR mutation","score":0.9002},{"id":"https://openalex.org/keywords/bone-marrow-fibrosis","display_name":"bone marrow fibrosis","score":0.4882},{"id":"https://openalex.org/keywords/mpl-mutation","display_name":"MPL mutation","score":0.9207},{"id":"https://openalex.org/keywords/erythrocytosis","display_name":"erythrocytosis","score":0.2837},{"id":"https://openalex.org/keywords/jak2-inhibitors","display_name":"JAK2 inhibitors","score":0.5117},{"id":"https://openalex.org/keywords/cytoreductive-therapy","display_name":"cytoreductive therapy","score":0.5913},{"id":"https://openalex.org/keywords/leukemic-transformation","display_name":"leukemic transformation","score":0.2258},{"id":"https://openalex.org/keywords/philadelphia-chromosome-negative-myeloproliferative-neoplasms","display_name":"Philadelphia-negative myeloproliferative neoplasms","score":0.9058},{"id":"https://openalex.org/keywords/anagrelide","display_name":"anagrelide","score":0.5994},{"id":"https://openalex.org/keywords/secondary-myelofibrosis","display_name":"secondary myelofibrosis","score":0.8433},{"id":"https://openalex.org/keywords/jak1-2-inhibitor","display_name":"JAK1/2 inhibitor","score":0.4454},{"id":"https://openalex.org/keywords/allele-burden","display_name":"allele burden","score":0.8509},{"id":"https://openalex.org/keywords/jak2-exon-12-mutation","display_name":"JAK2 exon 12 mutation","score":0.9726},{"id":"https://openalex.org/keywords/myelofibrosis-with-myeloid-metaplasia","display_name":"myelofibrosis with myeloid metaplasia","score":0.7542},{"id":"https://openalex.org/keywords/myeloid-metaplasia","display_name":"myeloid metaplasia","score":0.4699},{"id":"https://openalex.org/keywords/post-polycythemia-vera-myelofibrosis","display_name":"post-polycythemia vera myelofibrosis","score":0.9742},{"id":"https://openalex.org/keywords/chronic-neutrophilic-leukemia","display_name":"chronic neutrophilic leukemia","score":0.581}],"legacy_keywords":"JAK2 Mutation; Myelofibrosis; Polycythemia Vera; Thrombocythemia; CALR Mutation; Prognostic Scoring System; Ruxolitinib Therapy; Hematologic Response; Leukemic Transformation; Stem Cell Transplantation","ids":{"openalex":"https://openalex.org/T11628","wikipedia":"https://en.wikipedia.org/wiki/Myeloproliferative_neoplasm"},"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"},"siblings":[{"id":"https://openalex.org/T10129","display_name":"Glioma Diagnosis and Treatment"},{"id":"https://openalex.org/T10176","display_name":"Mesenchymal stem cell research"},{"id":"https://openalex.org/T10554","display_name":"Hemoglobinopathies and Related Disorders"},{"id":"https://openalex.org/T11157","display_name":"Chronic Lymphocytic Leukemia Research"},{"id":"https://openalex.org/T11917","display_name":"Coagulation, Bradykinin, Polyphosphates, and Angioedema"},{"id":"https://openalex.org/T12199","display_name":"Vascular Anomalies and Treatments"},{"id":"https://openalex.org/T12400","display_name":"Neurogenetic and Muscular Disorders Research"},{"id":"https://openalex.org/T13738","display_name":"Congenital Ear and Nasal Anomalies"}],"works_count":36494,"cited_by_count":453996,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T11628","updated_date":"2026-10-21T03:01:35","created_date":"2024-01-23T15:27:11"}