{"id":"https://openalex.org/T11547","display_name":"Sesquiterpenes and Asteraceae Studies","description":"This cluster of papers explores the biological activities of sesquiterpene lactones, particularly their potential in cancer treatment. The research covers apoptosis induction, anti-inflammatory effects, NF-?B inhibition, pharmacological properties, and the chemistry of sesquiterpene lactones derived from various medicinal plants. Additionally, it investigates the potential of compounds like thapsigargin in cancer therapy.","keywords":[{"id":"https://openalex.org/keywords/sesquiterpene-lactones","display_name":"sesquiterpene lactones","score":0.2972},{"id":"https://openalex.org/keywords/guaianolides","display_name":"guaianolides","score":0.6414},{"id":"https://openalex.org/keywords/sesquiterpene-esters","display_name":"sesquiterpene esters","score":0.8705},{"id":"https://openalex.org/keywords/parthenolide","display_name":"parthenolide","score":0.3967},{"id":"https://openalex.org/keywords/germacranolides","display_name":"germacranolides","score":0.8742},{"id":"https://openalex.org/keywords/eudesmanolides","display_name":"eudesmanolides","score":0.7902},{"id":"https://openalex.org/keywords/furanoeremophilanes","display_name":"furanoeremophilanes","score":0.9067},{"id":"https://openalex.org/keywords/eudesmane-sesquiterpenoids","display_name":"eudesmane sesquiterpenes","score":0.4999},{"id":"https://openalex.org/keywords/costunolide","display_name":"costunolide","score":0.4575},{"id":"https://openalex.org/keywords/monoesters","display_name":"monoesters","score":0.3967},{"id":"https://openalex.org/keywords/bicyclic-sesquiterpenes","display_name":"bicyclic sesquiterpenes","score":0.4285},{"id":"https://openalex.org/keywords/bicyclic-sesquiterpene-esters","display_name":"bicyclic sesquiterpene esters","score":0.9751},{"id":"https://openalex.org/keywords/alantolactone","display_name":"alantolactone","score":0.535},{"id":"https://openalex.org/keywords/dehydrocostus-lactone","display_name":"dehydrocostus lactone","score":0.438},{"id":"https://openalex.org/keywords/pseudoguaianolides","display_name":"pseudoguaianolides","score":0.8089},{"id":"https://openalex.org/keywords/eremophilane-sesquiterpenes","display_name":"eremophilane sesquiterpenes","score":0.5961},{"id":"https://openalex.org/keywords/eremophilanes","display_name":"eremophilanes","score":0.7957},{"id":"https://openalex.org/keywords/santonin","display_name":"santonin","score":0.2196},{"id":"https://openalex.org/keywords/eudesmanes","display_name":"eudesmanes","score":0.6473},{"id":"https://openalex.org/keywords/isoalantolactone","display_name":"isoalantolactone","score":0.5501},{"id":"https://openalex.org/keywords/tricyclic-sesquiterpene-esters","display_name":"tricyclic sesquiterpene esters","score":0.9938},{"id":"https://openalex.org/keywords/helenalin","display_name":"helenalin","score":0.4435},{"id":"https://openalex.org/keywords/guaiane-sesquiterpenes","display_name":"guaiane sesquiterpenes","score":0.4689},{"id":"https://openalex.org/keywords/saussurea-lappa","display_name":"Saussurea lappa","score":0.22},{"id":"https://openalex.org/keywords/alpha-methylene-gamma-lactones","display_name":"\u03b1-methylene-\u03b3-lactones","score":0.3566}],"legacy_keywords":"Sesquiterpene Lactones; Cancer; Apoptosis; Anti-inflammatory; NF-?B; Pharmacology; Chemistry; Antioxidant; Medicinal Plants; Thapsigargin","ids":{"openalex":"https://openalex.org/T11547","wikipedia":"https://en.wikipedia.org/wiki/Sesquiterpene_lactone"},"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"},"siblings":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation"},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies"},{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment"},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research"},{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms"},{"id":"https://openalex.org/T10631","display_name":"Cancer, Hypoxia, and Metabolism"},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics"},{"id":"https://openalex.org/T11591","display_name":"NF-\u03baB Signaling Pathways"},{"id":"https://openalex.org/T12465","display_name":"Cancer, Lipids, and Metabolism"},{"id":"https://openalex.org/T13350","display_name":"Myxozoan Parasites in Aquatic Species"},{"id":"https://openalex.org/T13943","display_name":"Beetle Biology and Toxicology Studies"},{"id":"https://openalex.org/T13971","display_name":"Synthesis and Biological Activity"}],"works_count":25283,"cited_by_count":319552,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T11547","updated_date":"2026-10-17T03:02:00","created_date":"2024-01-23T15:27:11"}