{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy","description":"This cluster of papers explores the immunological mechanisms involved in pregnancy, focusing on the interactions at the fetal-maternal interface, including the roles of decidual NK cells, regulatory T cells, HLA-G, and the Th1/Th2 paradigm. It delves into topics such as implantation, recurrent pregnancy loss, maternal-fetal tolerance, and endometrial receptivity.","keywords":[{"id":"https://openalex.org/keywords/recurrent-pregnancy-loss","display_name":"recurrent pregnancy loss","score":0.3909},{"id":"https://openalex.org/keywords/endometrium","display_name":"endometrium","score":0.2318},{"id":"https://openalex.org/keywords/embryo-implantation","display_name":"embryo implantation","score":0.3964},{"id":"https://openalex.org/keywords/endometrial-receptivity","display_name":"endometrial receptivity","score":0.376},{"id":"https://openalex.org/keywords/trophoblast","display_name":"trophoblast","score":0.2369},{"id":"https://openalex.org/keywords/decidua","display_name":"decidua","score":0.525},{"id":"https://openalex.org/keywords/maternal-fetal-immune-tolerance","display_name":"maternal-fetal immune tolerance","score":0.7059},{"id":"https://openalex.org/keywords/maternal-fetal-interface","display_name":"maternal-fetal interface","score":0.4583},{"id":"https://openalex.org/keywords/implantation","display_name":"implantation","score":0.2943},{"id":"https://openalex.org/keywords/decidualization","display_name":"decidualization","score":0.6093},{"id":"https://openalex.org/keywords/pregnancy-immunology","display_name":"pregnancy immunology","score":0.7382},{"id":"https://openalex.org/keywords/recurrent-implantation-failure","display_name":"recurrent implantation failure","score":0.5775},{"id":"https://openalex.org/keywords/endometrial-stromal-cells","display_name":"endometrial stromal cells","score":0.3277},{"id":"https://openalex.org/keywords/trophoblast-invasion","display_name":"trophoblast invasion","score":0.2553},{"id":"https://openalex.org/keywords/implantation-failure","display_name":"implantation failure","score":0.4355},{"id":"https://openalex.org/keywords/hla-g","display_name":"HLA-G","score":0.3152},{"id":"https://openalex.org/keywords/early-pregnancy-loss","display_name":"early pregnancy loss","score":0.2589},{"id":"https://openalex.org/keywords/threatened-abortion","display_name":"threatened abortion","score":0.2714},{"id":"https://openalex.org/keywords/reproductive-immunology","display_name":"reproductive immunology","score":0.6186},{"id":"https://openalex.org/keywords/window-of-implantation","display_name":"implantation window","score":0.6701},{"id":"https://openalex.org/keywords/pregnancy-maintenance","display_name":"pregnancy maintenance","score":0.3148},{"id":"https://openalex.org/keywords/uterine-natural-killer-cells","display_name":"uterine natural killer cells","score":0.7725},{"id":"https://openalex.org/keywords/decidual-cells","display_name":"decidual cells","score":0.4939},{"id":"https://openalex.org/keywords/unexplained-recurrent-miscarriage","display_name":"unexplained recurrent spontaneous abortion","score":0.8142},{"id":"https://openalex.org/keywords/extravillous-trophoblast","display_name":"extravillous trophoblast","score":0.2557}],"legacy_keywords":"Decidual NK Cells; Regulatory T Cells; Fetal-Maternal Interface; Implantation; Recurrent Pregnancy Loss; Maternal-Fetal Tolerance; HLA-G; Th1/Th2 Paradigm; Endometrial Receptivity; Immune Regulation","ids":{"openalex":"https://openalex.org/T11510","wikipedia":"https://en.wikipedia.org/wiki/Immunology_of_pregnancy"},"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"},"siblings":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology"},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation"},{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis"},{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota"},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses"},{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases"},{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction"},{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer"},{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine"},{"id":"https://openalex.org/T11403","display_name":"Invertebrate Immune Response Mechanisms"},{"id":"https://openalex.org/T11597","display_name":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms"},{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses"},{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders"},{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies"},{"id":"https://openalex.org/T12255","display_name":"Biosimilars and Bioanalytical Methods"},{"id":"https://openalex.org/T12387","display_name":"Galectins and Cancer Biology"},{"id":"https://openalex.org/T12477","display_name":"Toxin Mechanisms and Immunotoxins"},{"id":"https://openalex.org/T12528","display_name":"IL-33, ST2, and ILC Pathways"},{"id":"https://openalex.org/T12672","display_name":"Phagocytosis and Immune Regulation"},{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases"},{"id":"https://openalex.org/T13254","display_name":"Macrophage Migration Inhibitory Factor"},{"id":"https://openalex.org/T13410","display_name":"Immune responses and vaccinations"},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses"},{"id":"https://openalex.org/T14165","display_name":"Inflammation biomarkers and pathways"},{"id":"https://openalex.org/T14245","display_name":"Biomarkers in Disease Mechanisms"}],"works_count":66092,"cited_by_count":1016468,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T11510","updated_date":"2026-10-21T03:01:35","created_date":"2024-01-23T15:27:10"}