{"id":"https://openalex.org/T11288","display_name":"Clostridium difficile and Clostridium perfringens research","description":"This cluster of papers focuses on the epidemiology, treatment, and prevention of Clostridium difficile infection, with a particular emphasis on fecal microbiota transplantation, antibiotic-associated diarrhea, healthcare-associated infections, toxin production, and clinical practice guidelines. It also explores the role of microbiome diversity, vancomycin and metronidazole treatment, risk factors for infection, and bacterial toxins associated with the disease.","keywords":[{"id":"https://openalex.org/keywords/clostridium-difficile-infection","display_name":"Clostridium difficile infection","score":0.7112},{"id":"https://openalex.org/keywords/clostridioides-difficile","display_name":"Clostridium difficile","score":0.6432},{"id":"https://openalex.org/keywords/clostridium-perfringens","display_name":"Clostridium perfringens","score":0.4933},{"id":"https://openalex.org/keywords/antibiotic-associated-diarrhea","display_name":"antibiotic-associated diarrhea","score":0.5865},{"id":"https://openalex.org/keywords/clostridium","display_name":"Clostridium","score":0.2223},{"id":"https://openalex.org/keywords/pseudomembranous-colitis","display_name":"pseudomembranous colitis","score":0.7087},{"id":"https://openalex.org/keywords/recurrent-clostridioides-difficile-infection","display_name":"recurrent Clostridium difficile infection","score":0.9},{"id":"https://openalex.org/keywords/gas-gangrene","display_name":"gas gangrene","score":0.6072},{"id":"https://openalex.org/keywords/clostridium-difficile-associated-diarrhea","display_name":"Clostridium difficile-associated diarrhea","score":0.7272},{"id":"https://openalex.org/keywords/toxin-b","display_name":"toxin B","score":0.8814},{"id":"https://openalex.org/keywords/clostridium-septicum","display_name":"Clostridium septicum","score":0.8082},{"id":"https://openalex.org/keywords/toxin-a","display_name":"toxin A","score":0.8598},{"id":"https://openalex.org/keywords/fidaxomicin","display_name":"fidaxomicin","score":0.8306},{"id":"https://openalex.org/keywords/clostridium-infection","display_name":"clostridial infection","score":0.6435},{"id":"https://openalex.org/keywords/clostridium-perfringens-type-a","display_name":"Clostridium perfringens type A","score":0.8605},{"id":"https://openalex.org/keywords/alpha-toxin","display_name":"alpha-toxin","score":0.466},{"id":"https://openalex.org/keywords/enterotoxemia","display_name":"enterotoxemia","score":0.5445},{"id":"https://openalex.org/keywords/necrotic-enteritis","display_name":"necrotic enteritis","score":0.4097},{"id":"https://openalex.org/keywords/clostridium-tetani","display_name":"Clostridium tetani","score":0.2499},{"id":"https://openalex.org/keywords/clostridium-difficile-toxin","display_name":"Clostridium difficile toxin","score":0.7199},{"id":"https://openalex.org/keywords/ribotype-027","display_name":"ribotype 027","score":0.9505},{"id":"https://openalex.org/keywords/clostridium-difficile-colitis","display_name":"Clostridium difficile colitis","score":0.5631},{"id":"https://openalex.org/keywords/antibiotic-associated-colitis","display_name":"antibiotic-associated colitis","score":0.6591},{"id":"https://openalex.org/keywords/nosocomial-diarrhea","display_name":"nosocomial diarrhea","score":0.7247},{"id":"https://openalex.org/keywords/clostridium-tertium","display_name":"Clostridium tertium","score":0.8008}],"legacy_keywords":"Fecal Microbiota Transplantation; Antibiotic-Associated Diarrhea; Healthcare-Associated Infections; Toxin Production; Epidemiology; Clinical Practice Guidelines; Microbiome Diversity; Vancomycin and Metronidazole Treatment; Risk Factors; Bacterial Toxins","ids":{"openalex":"https://openalex.org/T11288","wikipedia":"https://en.wikipedia.org/wiki/Clostridioides_difficile_infection"},"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"},"siblings":[{"id":"https://openalex.org/T10038","display_name":"Tuberculosis Research and Epidemiology"},{"id":"https://openalex.org/T10041","display_name":"COVID-19 Clinical Research Studies"},{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions"},{"id":"https://openalex.org/T10118","display_name":"SARS-CoV-2 and COVID-19 Research"},{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility"},{"id":"https://openalex.org/T10195","display_name":"Antimicrobial Resistance in Staphylococcus"},{"id":"https://openalex.org/T10526","display_name":"HIV/AIDS drug development and treatment"},{"id":"https://openalex.org/T10976","display_name":"Viral gastroenteritis research and epidemiology"},{"id":"https://openalex.org/T11000","display_name":"Infection Control in Healthcare"},{"id":"https://openalex.org/T11581","display_name":"Viral Infections and Outbreaks Research"},{"id":"https://openalex.org/T11702","display_name":"Parasitic Diseases Research and Treatment"},{"id":"https://openalex.org/T11754","display_name":"SARS-CoV-2 detection and testing"},{"id":"https://openalex.org/T12047","display_name":"Viral Infections and Vectors"},{"id":"https://openalex.org/T12107","display_name":"Leprosy Research and Treatment"},{"id":"https://openalex.org/T12116","display_name":"Dermatological diseases and infestations"},{"id":"https://openalex.org/T12297","display_name":"Otolaryngology and Infectious Diseases"},{"id":"https://openalex.org/T12463","display_name":"Amoebic Infections and Treatments"},{"id":"https://openalex.org/T12849","display_name":"Parvovirus B19 Infection Studies"},{"id":"https://openalex.org/T12914","display_name":"Infectious Disease Case Reports and Treatments"},{"id":"https://openalex.org/T13201","display_name":"Infectious Encephalopathies and Encephalitis"}],"works_count":68464,"cited_by_count":822133,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T11288","updated_date":"2026-10-16T03:01:39","created_date":"2024-01-23T15:27:10"}