{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics","description":"This cluster of papers focuses on the genomic landscape of cancer, mutational signatures, intratumor heterogeneity, liquid biopsies, somatic mutations, tumor evolution, cell-free DNA, genomic instability, targeted therapy, and clonal evolution in various cancer types.","keywords":[{"id":"https://openalex.org/keywords/liquid-biopsy","display_name":"liquid biopsy","score":0.3183},{"id":"https://openalex.org/keywords/circulating-tumor-dna","display_name":"circulating tumor DNA","score":0.3916},{"id":"https://openalex.org/keywords/cancer-genomics","display_name":"cancer genomics","score":0.4032},{"id":"https://openalex.org/keywords/cell-free-dna","display_name":"cell-free DNA","score":0.3595},{"id":"https://openalex.org/keywords/circulating-tumor-cells","display_name":"circulating tumor cells","score":0.2061},{"id":"https://openalex.org/keywords/copy-number-alterations","display_name":"copy number alterations","score":0.2046},{"id":"https://openalex.org/keywords/tumor-evolution","display_name":"tumor evolution","score":0.3022},{"id":"https://openalex.org/keywords/driver-mutations","display_name":"driver mutations","score":0.2475},{"id":"https://openalex.org/keywords/mutational-signatures","display_name":"mutational signatures","score":0.3508},{"id":"https://openalex.org/keywords/variant-allele-frequency","display_name":"variant allele frequency","score":0.2463},{"id":"https://openalex.org/keywords/actionable-mutations","display_name":"actionable mutations","score":0.3746},{"id":"https://openalex.org/keywords/mutation-significance","display_name":"mutation significance","score":0.9856},{"id":"https://openalex.org/keywords/comprehensive-genomic-profiling","display_name":"comprehensive genomic profiling","score":0.2761},{"id":"https://openalex.org/keywords/cancer-driver-genes","display_name":"cancer driver genes","score":0.3521},{"id":"https://openalex.org/keywords/tumor-genomic-profiling","display_name":"tumor genomic profiling","score":0.3714},{"id":"https://openalex.org/keywords/cellsearch","display_name":"CellSearch","score":0.3342},{"id":"https://openalex.org/keywords/molecular-tumor-board","display_name":"molecular tumor board","score":0.4107},{"id":"https://openalex.org/keywords/plasma-dna","display_name":"plasma DNA","score":0.3231},{"id":"https://openalex.org/keywords/tumor-mutations","display_name":"cancer mutations","score":0.2176},{"id":"https://openalex.org/keywords/somatic-copy-number-alterations","display_name":"somatic copy number alterations","score":0.3044},{"id":"https://openalex.org/keywords/passenger-mutations","display_name":"passenger mutations","score":0.5132},{"id":"https://openalex.org/keywords/mutsig","display_name":"MutSig","score":0.9337},{"id":"https://openalex.org/keywords/mutsigcv","display_name":"MutSigCV","score":0.9064},{"id":"https://openalex.org/keywords/tumor-molecular-profiling","display_name":"tumor molecular profiling","score":0.3162},{"id":"https://openalex.org/keywords/plasma-cell-free-dna","display_name":"plasma cell-free DNA","score":0.3595}],"legacy_keywords":"Cancer Genomics; Mutational Signatures; Intratumor Heterogeneity; Liquid Biopsies; Somatic Mutations; Tumor Evolution; Cell-Free DNA; Genomic Instability; Targeted Therapy; Clonal Evolution","ids":{"openalex":"https://openalex.org/T11287","wikipedia":"https://en.wikipedia.org/wiki/Cancer_genomics"},"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"},"siblings":[{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation"},{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies"},{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment"},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research"},{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms"},{"id":"https://openalex.org/T10631","display_name":"Cancer, Hypoxia, and Metabolism"},{"id":"https://openalex.org/T11547","display_name":"Sesquiterpenes and Asteraceae Studies"},{"id":"https://openalex.org/T11591","display_name":"NF-\u03baB Signaling Pathways"},{"id":"https://openalex.org/T12465","display_name":"Cancer, Lipids, and Metabolism"},{"id":"https://openalex.org/T13350","display_name":"Myxozoan Parasites in Aquatic Species"},{"id":"https://openalex.org/T13943","display_name":"Beetle Biology and Toxicology Studies"},{"id":"https://openalex.org/T13971","display_name":"Synthesis and Biological Activity"}],"works_count":71838,"cited_by_count":1405936,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T11287","updated_date":"2026-10-16T03:01:39","created_date":"2024-01-23T15:27:10"}