{"id":"https://openalex.org/T11131","display_name":"Proteoglycans and glycosaminoglycans research","description":"This cluster of papers explores the role of extracellular matrix components such as hyaluronan, proteoglycans, and heparan sulfate in regulating cell signaling, synaptic plasticity, inflammation, and angiogenesis. It delves into the molecular interactions and functions of these matrix molecules in various biological processes.","keywords":[{"id":"https://openalex.org/keywords/glycosaminoglycans","display_name":"glycosaminoglycans","score":0.3047},{"id":"https://openalex.org/keywords/chondroitin-sulfate","display_name":"chondroitin sulfate","score":0.3846},{"id":"https://openalex.org/keywords/heparan-sulfate","display_name":"heparan sulfate","score":0.4302},{"id":"https://openalex.org/keywords/proteoglycans","display_name":"proteoglycans","score":0.3227},{"id":"https://openalex.org/keywords/hyaluronidase","display_name":"hyaluronidase","score":0.2455},{"id":"https://openalex.org/keywords/heparan-sulfate-proteoglycans","display_name":"heparan sulfate proteoglycans","score":0.3759},{"id":"https://openalex.org/keywords/dermatan-sulfate","display_name":"dermatan sulfate","score":0.5225},{"id":"https://openalex.org/keywords/glycosaminoglycan-biosynthesis","display_name":"glycosaminoglycan synthesis","score":0.4784},{"id":"https://openalex.org/keywords/heparanase","display_name":"heparanase","score":0.4084},{"id":"https://openalex.org/keywords/chondroitin-sulfate-proteoglycans","display_name":"chondroitin sulfate proteoglycans","score":0.4004},{"id":"https://openalex.org/keywords/keratan-sulfate","display_name":"keratan sulfate","score":0.4696},{"id":"https://openalex.org/keywords/proteoglycan-synthesis","display_name":"proteoglycan synthesis","score":0.3094},{"id":"https://openalex.org/keywords/sulfated-glycosaminoglycans","display_name":"sulfated glycosaminoglycans","score":0.3343},{"id":"https://openalex.org/keywords/hyaluronan-synthesis","display_name":"hyaluronan synthesis","score":0.5933},{"id":"https://openalex.org/keywords/chondroitinase-abc","display_name":"chondroitinase ABC","score":0.4069},{"id":"https://openalex.org/keywords/versican","display_name":"versican","score":0.2906},{"id":"https://openalex.org/keywords/hyaluronan-synthase","display_name":"hyaluronan synthase","score":0.604},{"id":"https://openalex.org/keywords/perlecan","display_name":"perlecan","score":0.3251},{"id":"https://openalex.org/keywords/biglycan","display_name":"biglycan","score":0.2863},{"id":"https://openalex.org/keywords/chondroitin-4-sulfate","display_name":"chondroitin 4-sulfate","score":0.5664},{"id":"https://openalex.org/keywords/hyaluronan-synthase-2","display_name":"HAS2","score":0.3725},{"id":"https://openalex.org/keywords/syndecan-4","display_name":"syndecan-4","score":0.3181},{"id":"https://openalex.org/keywords/hyaluronic-acid-degradation","display_name":"hyaluronan degradation","score":0.5632},{"id":"https://openalex.org/keywords/hyaluronan-receptor","display_name":"hyaluronan receptor","score":0.5371},{"id":"https://openalex.org/keywords/chondroitin-6-sulfate","display_name":"chondroitin-6-sulfate","score":0.4843}],"legacy_keywords":"Hyaluronan; Proteoglycans; Heparan Sulfate; CD44; Cell Signaling; Glycosaminoglycans; Toll-like Receptors; Synaptic Plasticity; Inflammation; Angiogenesis","ids":{"openalex":"https://openalex.org/T11131","wikipedia":"https://en.wikipedia.org/wiki/Extracellular_matrix"},"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"},"siblings":[{"id":"https://openalex.org/T10379","display_name":"Cellular Mechanics and Interactions"},{"id":"https://openalex.org/T10492","display_name":"Microtubule and mitosis dynamics"},{"id":"https://openalex.org/T10617","display_name":"Cellular transport and secretion"},{"id":"https://openalex.org/T10825","display_name":"Plant Pathogens and Fungal Diseases"},{"id":"https://openalex.org/T11144","display_name":"melanin and skin pigmentation"},{"id":"https://openalex.org/T11150","display_name":"Endoplasmic Reticulum Stress and Disease"},{"id":"https://openalex.org/T11399","display_name":"Muscle metabolism and nutrition"},{"id":"https://openalex.org/T11650","display_name":"Skin and Cellular Biology Research"},{"id":"https://openalex.org/T11685","display_name":"Zebrafish Biomedical Research Applications"},{"id":"https://openalex.org/T12065","display_name":"Hippo pathway signaling and YAP/TAZ"},{"id":"https://openalex.org/T12094","display_name":"Hemoglobin structure and function"},{"id":"https://openalex.org/T12533","display_name":"Aldose Reductase and Taurine"},{"id":"https://openalex.org/T12712","display_name":"Myofascial pain diagnosis and treatment"},{"id":"https://openalex.org/T12793","display_name":"Caveolin-1 and cellular processes"},{"id":"https://openalex.org/T13127","display_name":"Biotin and Related Studies"},{"id":"https://openalex.org/T13637","display_name":"Calpain Protease Function and Regulation"}],"works_count":52443,"cited_by_count":1442792,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T11131","updated_date":"2026-10-22T03:01:35","created_date":"2024-01-23T15:27:09"}