{"id":"https://openalex.org/T11078","display_name":"Inflammasome and immune disorders","description":"This cluster of papers focuses on the molecular mechanisms of inflammasome activation, regulation, and its role in inflammatory responses, cell death (pyroptosis), and immune-related diseases. 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activation","score":0.5874},{"id":"https://openalex.org/keywords/asc","display_name":"ASC","score":0.5549},{"id":"https://openalex.org/keywords/mefv-gene","display_name":"MEFV gene","score":0.7366},{"id":"https://openalex.org/keywords/cryopyrin-associated-periodic-syndromes","display_name":"cryopyrin-associated periodic syndromes","score":0.8713},{"id":"https://openalex.org/keywords/periodic-fever","display_name":"periodic fever","score":0.5405},{"id":"https://openalex.org/keywords/caspase-1-activation","display_name":"caspase-1 activation","score":0.7473},{"id":"https://openalex.org/keywords/caspase-11","display_name":"caspase-11","score":0.5525},{"id":"https://openalex.org/keywords/nlrp3","display_name":"NLRP3","score":0.4468},{"id":"https://openalex.org/keywords/recurrent-fever","display_name":"recurrent fever","score":0.2536},{"id":"https://openalex.org/keywords/periodic-fever-syndromes","display_name":"periodic fever syndromes","score":0.7305},{"id":"https://openalex.org/keywords/canakinumab","display_name":"canakinumab","score":0.3261},{"id":"https://openalex.org/keywords/pfapa-syndrome","display_name":"PFAPA syndrome","score":0.6878},{"id":"https://openalex.org/keywords/il-1beta-secretion","display_name":"IL-1\u03b2 secretion","score":0.6371},{"id":"https://openalex.org/keywords/mefv-mutations","display_name":"MEFV mutations","score":0.7309},{"id":"https://openalex.org/keywords/pyrin","display_name":"pyrin","score":0.8611},{"id":"https://openalex.org/keywords/nod-like-receptors","display_name":"NOD-like receptors","score":0.2085},{"id":"https://openalex.org/keywords/mcc950","display_name":"MCC950","score":0.4276},{"id":"https://openalex.org/keywords/muckle-wells-syndrome","display_name":"Muckle-Wells syndrome","score":0.8372}],"legacy_keywords":"Inflammasome; NLRP3; Pyroptosis; Interleukin-1; Caspase-1; Inflammation; Cell Death; Immune Response; Mitochondria; Autoinflammatory Diseases","ids":{"openalex":"https://openalex.org/T11078","wikipedia":"https://en.wikipedia.org/wiki/Inflammasome"},"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"},"siblings":[{"id":"https://openalex.org/T10015","display_name":"Genomics and Phylogenetic Studies"},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics"},{"id":"https://openalex.org/T10066","display_name":"Gut microbiota and health"},{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms"},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling"},{"id":"https://openalex.org/T10207","display_name":"Advanced biosensing and bioanalysis techniques"},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics"},{"id":"https://openalex.org/T10240","display_name":"Plant tissue culture and regeneration"},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation"},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation"},{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation"},{"id":"https://openalex.org/T10301","display_name":"Mitochondrial Function and Pathology"},{"id":"https://openalex.org/T10303","display_name":"Photosynthetic Processes and Mechanisms"},{"id":"https://openalex.org/T10404","display_name":"Enzyme Catalysis and Immobilization"},{"id":"https://openalex.org/T10407","display_name":"Lipid Membrane Structure and Behavior"},{"id":"https://openalex.org/T10422","display_name":"Angiogenesis and VEGF in Cancer"},{"id":"https://openalex.org/T10432","display_name":"DNA and Nucleic Acid Chemistry"},{"id":"https://openalex.org/T10441","display_name":"Muscle Physiology 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