{"id":"https://openalex.org/T11036","display_name":"Antibiotics Pharmacokinetics and Efficacy","description":"This cluster of papers focuses on the pharmacokinetics of antibiotics, particularly in critically ill patients. It covers topics such as drug dosing, antimicrobial resistance, therapeutic drug monitoring, and the impact of factors like augmented renal clearance on antibiotic levels in the body.","keywords":[{"id":"https://openalex.org/keywords/cephalosporins","display_name":"cephalosporins","score":0.2528},{"id":"https://openalex.org/keywords/aminoglycosides","display_name":"aminoglycosides","score":0.2186},{"id":"https://openalex.org/keywords/serum-drug-levels","display_name":"serum drug concentration","score":0.2557},{"id":"https://openalex.org/keywords/antibiotic-dosing","display_name":"antibiotic dosing","score":0.5529},{"id":"https://openalex.org/keywords/carbapenems","display_name":"carbapenems","score":0.2055},{"id":"https://openalex.org/keywords/trough-concentration","display_name":"trough concentration","score":0.2194},{"id":"https://openalex.org/keywords/antibiotic-pharmacokinetics","display_name":"antibiotic pharmacokinetics","score":0.6328},{"id":"https://openalex.org/keywords/piperacillin","display_name":"piperacillin","score":0.2579},{"id":"https://openalex.org/keywords/population-pharmacokinetic-model","display_name":"population pharmacokinetic model","score":0.2023},{"id":"https://openalex.org/keywords/loading-dose","display_name":"loading dose","score":0.2027},{"id":"https://openalex.org/keywords/tissue-penetration","display_name":"tissue penetration","score":0.3099},{"id":"https://openalex.org/keywords/time-above-mic","display_name":"time above MIC","score":0.8592},{"id":"https://openalex.org/keywords/probability-of-target-attainment","display_name":"probability of target attainment","score":0.815},{"id":"https://openalex.org/keywords/pediatric-antibiotic-therapy","display_name":"pediatric antibiotic therapy","score":0.5426},{"id":"https://openalex.org/keywords/dosing-interval","display_name":"dosing interval","score":0.2059},{"id":"https://openalex.org/keywords/gram-positive-bacterial-infections","display_name":"Gram-positive bacterial infections","score":0.2107},{"id":"https://openalex.org/keywords/pharmacokinetics-pharmacodynamics","display_name":"pharmacokinetics/pharmacodynamics","score":0.2259},{"id":"https://openalex.org/keywords/antibiotic-dosing-regimens","display_name":"antibiotic dosing regimens","score":0.5184},{"id":"https://openalex.org/keywords/auc-mic-ratio","display_name":"AUC/MIC ratio","score":0.7236},{"id":"https://openalex.org/keywords/cefoperazone","display_name":"cefoperazone","score":0.2437},{"id":"https://openalex.org/keywords/prolonged-infusion","display_name":"prolonged infusion","score":0.397},{"id":"https://openalex.org/keywords/postantibiotic-effect","display_name":"post-antibiotic effect","score":0.4143},{"id":"https://openalex.org/keywords/netilmicin","display_name":"netilmicin","score":0.2824},{"id":"https://openalex.org/keywords/imipenem-cilastatin","display_name":"imipenem/cilastatin","score":0.2567},{"id":"https://openalex.org/keywords/oral-cephalosporins","display_name":"oral cephalosporins","score":0.4843}],"legacy_keywords":"Antibiotic Pharmacokinetics; Critically Ill Patients; Pharmacodynamic; Beta-lactam Antibiotics; Drug Dosing; Antimicrobial Resistance; Continuous Infusion; Aminoglycosides; Therapeutic Drug Monitoring; Augmented Renal Clearance","ids":{"openalex":"https://openalex.org/T11036","wikipedia":"https://en.wikipedia.org/wiki/Antibiotic_resistance"},"subfield":{"id":"https://openalex.org/subfields/2736","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"},"siblings":[{"id":"https://openalex.org/T10084","display_name":"Musculoskeletal pain and rehabilitation"},{"id":"https://openalex.org/T10252","display_name":"Microbial Natural Products and Biosynthesis"},{"id":"https://openalex.org/T10414","display_name":"Cannabis and Cannabinoid Research"},{"id":"https://openalex.org/T10678","display_name":"Inflammatory mediators and NSAID effects"},{"id":"https://openalex.org/T11071","display_name":"Treatment of Major Depression"},{"id":"https://openalex.org/T11085","display_name":"Fungal Biology and Applications"},{"id":"https://openalex.org/T11117","display_name":"Drug-Induced Adverse Reactions"},{"id":"https://openalex.org/T11264","display_name":"Coffee research and impacts"},{"id":"https://openalex.org/T12023","display_name":"Cholinesterase and Neurodegenerative Diseases"},{"id":"https://openalex.org/T12059","display_name":"Berberine and alkaloids research"},{"id":"https://openalex.org/T12539","display_name":"Pharmacology and Obesity Treatment"},{"id":"https://openalex.org/T12582","display_name":"Flavonoids in Medical Research"},{"id":"https://openalex.org/T13023","display_name":"Synthesis of Organic Compounds"},{"id":"https://openalex.org/T13130","display_name":"Biological and pharmacological studies of plants"},{"id":"https://openalex.org/T13335","display_name":"Pharmacological Effects of Medicinal Plants"},{"id":"https://openalex.org/T13365","display_name":"Medical and Biological Ozone Research"},{"id":"https://openalex.org/T13505","display_name":"Apelin-related biomedical research"},{"id":"https://openalex.org/T13767","display_name":"Leech Biology and Applications"},{"id":"https://openalex.org/T13809","display_name":"Philosophy, Health, and Society"},{"id":"https://openalex.org/T13921","display_name":"Biological Stains and Phytochemicals"},{"id":"https://openalex.org/T14028","display_name":"Healthcare and Venom Research"}],"works_count":88908,"cited_by_count":854515,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T11036","updated_date":"2026-10-20T03:01:21","created_date":"2024-01-23T15:27:09"}