{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","description":"This cluster of papers explores the role of natural killer (NK) cells in immunity, including their recognition mechanisms, activation, education, development, and potential for therapy. It covers topics such as NK cell receptors, immune inhibitory receptors, NKG2D immunoreceptor, and the use of NK cells in immunotherapy.","keywords":[{"id":"https://openalex.org/keywords/natural-killer-cells","display_name":"natural killer cells","score":0.3278},{"id":"https://openalex.org/keywords/nk-cell-cytotoxicity","display_name":"NK cell cytotoxicity","score":0.4685},{"id":"https://openalex.org/keywords/nk-cell-activation","display_name":"NK cell activation","score":0.6456},{"id":"https://openalex.org/keywords/nkg2d","display_name":"NKG2D","score":0.5999},{"id":"https://openalex.org/keywords/killer-cell-immunoglobulin-like-receptors","display_name":"killer cell immunoglobulin-like receptors","score":0.6646},{"id":"https://openalex.org/keywords/nk-cell-receptors","display_name":"NK cell receptors","score":0.7479},{"id":"https://openalex.org/keywords/nk-cell-therapy","display_name":"NK cell therapy","score":0.7126},{"id":"https://openalex.org/keywords/lymphokine-activated-killer-cells","display_name":"lymphokine-activated killer cells","score":0.4071},{"id":"https://openalex.org/keywords/perforin","display_name":"perforin","score":0.2039},{"id":"https://openalex.org/keywords/inhibitory-receptors","display_name":"inhibitory receptors","score":0.3737},{"id":"https://openalex.org/keywords/cd16","display_name":"CD16","score":0.2683},{"id":"https://openalex.org/keywords/nkg2d-ligands","display_name":"NKG2D ligands","score":0.6388},{"id":"https://openalex.org/keywords/nk-cell-expansion","display_name":"NK cell expansion","score":0.7795},{"id":"https://openalex.org/keywords/nkp46","display_name":"NKp46","score":0.6272},{"id":"https://openalex.org/keywords/nk-cell-subsets","display_name":"NK cell subsets","score":0.7205},{"id":"https://openalex.org/keywords/nk-cell-differentiation","display_name":"NK cell differentiation","score":0.7061},{"id":"https://openalex.org/keywords/nkg2a","display_name":"NKG2A","score":0.6517},{"id":"https://openalex.org/keywords/nk-cell-degranulation","display_name":"NK cell degranulation","score":0.6683},{"id":"https://openalex.org/keywords/nk-cell-proliferation","display_name":"NK cell proliferation","score":0.7243},{"id":"https://openalex.org/keywords/nk-cell-function","display_name":"NK cell function","score":0.6191},{"id":"https://openalex.org/keywords/nk-cell-development","display_name":"NK cell development","score":0.7829},{"id":"https://openalex.org/keywords/large-granular-lymphocytes","display_name":"large granular lymphocytes","score":0.4713},{"id":"https://openalex.org/keywords/nkp30","display_name":"NKp30","score":0.7341},{"id":"https://openalex.org/keywords/hla-e","display_name":"HLA-E","score":0.346},{"id":"https://openalex.org/keywords/nk-cell-dysfunction","display_name":"NK cell dysfunction","score":0.509}],"legacy_keywords":"Natural Killer Cells; NK Cell Recognition; Immune Inhibitory Receptors; NKG2D Immunoreceptor; NK Cell Activation; NK Cell Education; NK Cell Therapy; NK Cell Receptors; NK Cell Development; NK Cell Immunotherapy","ids":{"openalex":"https://openalex.org/T11020","wikipedia":"https://en.wikipedia.org/wiki/Natural_killer_cell"},"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"},"siblings":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology"},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation"},{"id":"https://openalex.org/T10469","display_name":"Psoriasis: Treatment and Pathogenesis"},{"id":"https://openalex.org/T10506","display_name":"Aquaculture disease management and microbiota"},{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses"},{"id":"https://openalex.org/T10993","display_name":"Complement system in diseases"},{"id":"https://openalex.org/T11313","display_name":"Immune cells in cancer"},{"id":"https://openalex.org/T11346","display_name":"Mast cells and histamine"},{"id":"https://openalex.org/T11403","display_name":"Invertebrate Immune Response Mechanisms"},{"id":"https://openalex.org/T11510","display_name":"Reproductive System and Pregnancy"},{"id":"https://openalex.org/T11597","display_name":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms"},{"id":"https://openalex.org/T11668","display_name":"interferon and immune responses"},{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders"},{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies"},{"id":"https://openalex.org/T12255","display_name":"Biosimilars and Bioanalytical Methods"},{"id":"https://openalex.org/T12387","display_name":"Galectins and Cancer Biology"},{"id":"https://openalex.org/T12477","display_name":"Toxin Mechanisms and Immunotoxins"},{"id":"https://openalex.org/T12528","display_name":"IL-33, ST2, and ILC Pathways"},{"id":"https://openalex.org/T12672","display_name":"Phagocytosis and Immune Regulation"},{"id":"https://openalex.org/T12955","display_name":"Atherosclerosis and Cardiovascular Diseases"},{"id":"https://openalex.org/T13254","display_name":"Macrophage Migration Inhibitory Factor"},{"id":"https://openalex.org/T13410","display_name":"Immune responses and vaccinations"},{"id":"https://openalex.org/T14072","display_name":"Immunotoxicology and immune responses"},{"id":"https://openalex.org/T14165","display_name":"Inflammation biomarkers and pathways"},{"id":"https://openalex.org/T14245","display_name":"Biomarkers in Disease Mechanisms"}],"works_count":51943,"cited_by_count":1416086,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T11020","updated_date":"2026-10-22T03:01:35","created_date":"2024-01-23T15:27:09"}