{"id":"https://openalex.org/T10817","display_name":"Multicomponent Synthesis of Heterocycles","description":"This cluster of papers focuses on recent advances in multicomponent reactions, particularly in the context of green chemistry, heterocyclic synthesis, catalysis, and organic synthesis. It explores the use of nanocatalysts, isocyanides, and asymmetric synthesis in the development of sustainable methodologies for drug discovery.","keywords":[{"id":"https://openalex.org/keywords/multicomponent-reactions","display_name":"multicomponent reactions","score":0.4656},{"id":"https://openalex.org/keywords/three-component-reaction","display_name":"three-component reaction","score":0.5048},{"id":"https://openalex.org/keywords/solvent-free-synthesis","display_name":"solvent-free synthesis","score":0.212},{"id":"https://openalex.org/keywords/aromatic-aldehydes","display_name":"aromatic aldehydes","score":0.2761},{"id":"https://openalex.org/keywords/malononitrile","display_name":"malononitrile","score":0.4331},{"id":"https://openalex.org/keywords/biginelli-reaction","display_name":"Biginelli reaction","score":0.7695},{"id":"https://openalex.org/keywords/one-pot-three-component-reaction","display_name":"one-pot three-component reaction","score":0.6809},{"id":"https://openalex.org/keywords/reusable-catalyst","display_name":"recyclable catalyst","score":0.2437},{"id":"https://openalex.org/keywords/ugi-reaction","display_name":"Ugi reaction","score":0.6158},{"id":"https://openalex.org/keywords/isocyanides","display_name":"isocyanides","score":0.2638},{"id":"https://openalex.org/keywords/dimedone","display_name":"dimedone","score":0.557},{"id":"https://openalex.org/keywords/catalyst-free-synthesis","display_name":"catalyst-free synthesis","score":0.2306},{"id":"https://openalex.org/keywords/one-pot-multicomponent-reaction","display_name":"one-pot multicomponent reaction","score":0.6935},{"id":"https://openalex.org/keywords/ammonium-acetate","display_name":"ammonium acetate","score":0.2985},{"id":"https://openalex.org/keywords/multicomponent-synthesis","display_name":"multicomponent synthesis","score":0.5251},{"id":"https://openalex.org/keywords/ethyl-acetoacetate","display_name":"ethyl acetoacetate","score":0.2726},{"id":"https://openalex.org/keywords/four-component-reaction","display_name":"four-component reaction","score":0.6614},{"id":"https://openalex.org/keywords/isatin","display_name":"isatin","score":0.2143},{"id":"https://openalex.org/keywords/3-4-dihydropyrimidin-2-1h-ones","display_name":"3,4-dihydropyrimidin-2(1H)-ones","score":0.8425},{"id":"https://openalex.org/keywords/magnetic-nanocatalyst","display_name":"magnetic nanocatalyst","score":0.3941},{"id":"https://openalex.org/keywords/4-hydroxycoumarin","display_name":"4-hydroxycoumarin","score":0.2878},{"id":"https://openalex.org/keywords/dihydropyrimidinones","display_name":"dihydropyrimidinones","score":0.5755},{"id":"https://openalex.org/keywords/spirooxindoles","display_name":"spirooxindoles","score":0.2006},{"id":"https://openalex.org/keywords/ethyl-cyanoacetate","display_name":"ethyl cyanoacetate","score":0.2297},{"id":"https://openalex.org/keywords/passerini-reaction","display_name":"Passerini reaction","score":0.524}],"legacy_keywords":"Multicomponent Reactions; Green Chemistry; Heterocyclic Synthesis; Catalysis; Organic Synthesis; Nanocatalysts; Isocyanides; Asymmetric Synthesis; Drug Discovery; Sustainable Methodologies","ids":{"openalex":"https://openalex.org/T10817","wikipedia":"https://en.wikipedia.org/wiki/Multicomponent_reaction"},"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"},"siblings":[{"id":"https://openalex.org/T10013","display_name":"Asymmetric Synthesis and Catalysis"},{"id":"https://openalex.org/T10092","display_name":"Organometallic Complex Synthesis and Catalysis"},{"id":"https://openalex.org/T10274","display_name":"Synthesis and biological activity"},{"id":"https://openalex.org/T10354","display_name":"Catalytic C\u2013H Functionalization Methods"},{"id":"https://openalex.org/T10405","display_name":"Advanced Polymer Synthesis and Characterization"},{"id":"https://openalex.org/T10548","display_name":"Catalytic Cross-Coupling Reactions"},{"id":"https://openalex.org/T10578","display_name":"Supramolecular Chemistry and Complexes"},{"id":"https://openalex.org/T10701","display_name":"Radical Photochemical Reactions"},{"id":"https://openalex.org/T10721","display_name":"Surfactants and Colloidal Systems"},{"id":"https://openalex.org/T10835","display_name":"Carbohydrate Chemistry and Synthesis"},{"id":"https://openalex.org/T10871","display_name":"Catalytic Alkyne Reactions"},{"id":"https://openalex.org/T10909","display_name":"Edible Oils Quality and Analysis"},{"id":"https://openalex.org/T10956","display_name":"Fullerene Chemistry and Applications"},{"id":"https://openalex.org/T11298","display_name":"Synthesis and Properties of Aromatic Compounds"},{"id":"https://openalex.org/T11440","display_name":"Click Chemistry and Applications"},{"id":"https://openalex.org/T11441","display_name":"Organoboron and organosilicon chemistry"},{"id":"https://openalex.org/T11549","display_name":"Synthetic Organic Chemistry Methods"},{"id":"https://openalex.org/T11611","display_name":"Cyclopropane Reaction Mechanisms"},{"id":"https://openalex.org/T11746","display_name":"Inorganic and Organometallic Chemistry"},{"id":"https://openalex.org/T11748","display_name":"Organophosphorus compounds synthesis"},{"id":"https://openalex.org/T11790","display_name":"N-Heterocyclic Carbenes in Organic and Inorganic Chemistry"},{"id":"https://openalex.org/T11831","display_name":"Chemical Synthesis and Reactions"},{"id":"https://openalex.org/T11989","display_name":"Oxidative Organic Chemistry Reactions"},{"id":"https://openalex.org/T12189","display_name":"Sulfur-Based Synthesis Techniques"},{"id":"https://openalex.org/T12191","display_name":"Chemical Reaction Mechanisms"},{"id":"https://openalex.org/T12228","display_name":"Coordination Chemistry and Organometallics"},{"id":"https://openalex.org/T12240","display_name":"Nanomaterials for catalytic reactions"},{"id":"https://openalex.org/T12251","display_name":"Synthesis and Catalytic Reactions"},{"id":"https://openalex.org/T12270","display_name":"Microwave-Assisted Synthesis and Applications"},{"id":"https://openalex.org/T12318","display_name":"Quinazolinone synthesis and applications"},{"id":"https://openalex.org/T12410","display_name":"Structural and Chemical Analysis of Organic and Inorganic Compounds"},{"id":"https://openalex.org/T12458","display_name":"Organometallic Compounds Synthesis and Characterization"},{"id":"https://openalex.org/T12526","display_name":"Antimicrobial agents and applications"},{"id":"https://openalex.org/T12527","display_name":"Chemistry and Stereochemistry Studies"},{"id":"https://openalex.org/T12562","display_name":"Synthesis and Characterization of Pyrroles"},{"id":"https://openalex.org/T12570","display_name":"Photopolymerization techniques and applications"},{"id":"https://openalex.org/T12653","display_name":"Cyclization and Aryne Chemistry"},{"id":"https://openalex.org/T12852","display_name":"Chemical Thermodynamics and Molecular Structure"},{"id":"https://openalex.org/T12893","display_name":"Organic Chemistry Cycloaddition Reactions"},{"id":"https://openalex.org/T12973","display_name":"Synthesis of Indole Derivatives"},{"id":"https://openalex.org/T13013","display_name":"Free Radicals and Antioxidants"},{"id":"https://openalex.org/T13105","display_name":"Synthesis and pharmacology of benzodiazepine derivatives"},{"id":"https://openalex.org/T13115","display_name":"Axial and Atropisomeric Chirality Synthesis"},{"id":"https://openalex.org/T13124","display_name":"Chemical synthesis and alkaloids"},{"id":"https://openalex.org/T13160","display_name":"Synthesis and Biological Evaluation"},{"id":"https://openalex.org/T13208","display_name":"Synthesis of heterocyclic compounds"},{"id":"https://openalex.org/T13230","display_name":"Synthesis and Reactivity of Heterocycles"},{"id":"https://openalex.org/T13239","display_name":"Phosphorus compounds and reactions"},{"id":"https://openalex.org/T13265","display_name":"Synthesis of Tetrazole Derivatives"},{"id":"https://openalex.org/T13304","display_name":"Synthesis and Reactivity of Sulfur-Containing Compounds"},{"id":"https://openalex.org/T13489","display_name":"Synthesis of \u03b2-Lactam Compounds"},{"id":"https://openalex.org/T13568","display_name":"Wood and Agarwood Research"},{"id":"https://openalex.org/T13649","display_name":"Advanced Synthetic Organic Chemistry"},{"id":"https://openalex.org/T13833","display_name":"Ferrocene Chemistry and Applications"},{"id":"https://openalex.org/T13859","display_name":"Organic Chemistry Synthesis Methods"},{"id":"https://openalex.org/T13876","display_name":"Chemical synthesis and pharmacological studies"},{"id":"https://openalex.org/T14099","display_name":"Synthesis and Characterization of Heterocyclic Compounds"},{"id":"https://openalex.org/T14297","display_name":"Plant-Derived Bioactive Compounds"},{"id":"https://openalex.org/T14318","display_name":"Polydiacetylene-based materials and applications"},{"id":"https://openalex.org/T14459","display_name":"Synthesis and Reactions of Organic Compounds"}],"works_count":44102,"cited_by_count":662044,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T10817","updated_date":"2026-10-22T03:01:35","created_date":"2024-01-23T15:27:08"}