{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","description":"This cluster of papers focuses on the incidence, risk factors, and management of viral-related cancers, particularly associated with Epstein-Barr virus (EBV) and Kaposi's Sarcoma-associated herpesvirus (KSHV), in immunocompromised individuals such as HIV/AIDS patients and transplant recipients. It explores the impact of immunosuppression, antiretroviral therapy, and viral reactivation on cancer development, as well as the use of targeted therapies and immune-based treatments for these malignancies.","keywords":[{"id":"https://openalex.org/keywords/epstein-barr-virus","display_name":"Epstein-Barr virus","score":0.5084},{"id":"https://openalex.org/keywords/kaposi-sarcoma","display_name":"Kaposi's sarcoma","score":0.6254},{"id":"https://openalex.org/keywords/infectious-mononucleosis","display_name":"infectious mononucleosis","score":0.6139},{"id":"https://openalex.org/keywords/human-herpesvirus-8","display_name":"human herpesvirus 8","score":0.79},{"id":"https://openalex.org/keywords/kaposi-s-sarcoma-associated-herpesvirus","display_name":"Kaposi's sarcoma-associated herpesvirus","score":0.7609},{"id":"https://openalex.org/keywords/viral-carcinogenesis","display_name":"viral oncogenesis","score":0.3125},{"id":"https://openalex.org/keywords/post-transplant-lymphoproliferative-disorder","display_name":"post-transplant lymphoproliferative disorder","score":0.5759},{"id":"https://openalex.org/keywords/burkitt-lymphoma","display_name":"Burkitt lymphoma","score":0.2294},{"id":"https://openalex.org/keywords/lymphoproliferative-disorders","display_name":"lymphoproliferative disorders","score":0.2004},{"id":"https://openalex.org/keywords/viral-latency","display_name":"viral latency","score":0.2165},{"id":"https://openalex.org/keywords/oncogenic-viruses","display_name":"oncogenic viruses","score":0.428},{"id":"https://openalex.org/keywords/primary-effusion-lymphoma","display_name":"primary effusion lymphoma","score":0.8318},{"id":"https://openalex.org/keywords/aids-associated-kaposi-s-sarcoma","display_name":"AIDS-related Kaposi's sarcoma","score":0.9132},{"id":"https://openalex.org/keywords/hiv-associated-lymphoma","display_name":"HIV-associated lymphoma","score":0.6318},{"id":"https://openalex.org/keywords/epstein-barr-virus-infection","display_name":"Epstein-Barr virus infection","score":0.3576},{"id":"https://openalex.org/keywords/latent-membrane-protein-1","display_name":"latent membrane protein 1","score":0.6092},{"id":"https://openalex.org/keywords/multicentric-castleman-disease","display_name":"multicentric Castleman disease","score":0.6553},{"id":"https://openalex.org/keywords/hiv-associated-malignancies","display_name":"HIV-associated malignancies","score":0.5959},{"id":"https://openalex.org/keywords/ebna1","display_name":"EBNA1","score":0.5879},{"id":"https://openalex.org/keywords/ebv-encoded-rna","display_name":"EBV-encoded RNA","score":0.6727},{"id":"https://openalex.org/keywords/gammaherpesviruses","display_name":"gammaherpesvirus","score":0.4847},{"id":"https://openalex.org/keywords/ebna2","display_name":"EBNA2","score":0.7417},{"id":"https://openalex.org/keywords/lmp1","display_name":"LMP1","score":0.5465},{"id":"https://openalex.org/keywords/viral-etiology-of-cancer","display_name":"viral etiology of cancer","score":0.4617},{"id":"https://openalex.org/keywords/plasmablastic-lymphoma","display_name":"plasmablastic lymphoma","score":0.472}],"legacy_keywords":"Epstein-Barr Virus; Kaposi's Sarcoma; HIV/AIDS; Transplant Recipients; Lymphoproliferative Disorders; Human Herpesvirus 8; Cancer Incidence; Immunosuppression; Post-Transplant Lymphoproliferative Disease; Viral Oncogenesis","ids":{"openalex":"https://openalex.org/T10685","wikipedia":"https://en.wikipedia.org/wiki/Epstein%E2%80%93Barr_virus-associated_lymphoproliferative_disease"},"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"},"siblings":[{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers"},{"id":"https://openalex.org/T10163","display_name":"Metal complexes synthesis and properties"},{"id":"https://openalex.org/T10178","display_name":"Cancer survivorship and care"},{"id":"https://openalex.org/T10231","display_name":"Pancreatic and Hepatic Oncology Research"},{"id":"https://openalex.org/T10335","display_name":"Colorectal Cancer Surgical Treatments"},{"id":"https://openalex.org/T10336","display_name":"Cancer Cells and Metastasis"},{"id":"https://openalex.org/T10392","display_name":"Cutaneous Melanoma Detection and Management"},{"id":"https://openalex.org/T10552","display_name":"Colorectal Cancer Screening and Detection"},{"id":"https://openalex.org/T10556","display_name":"Global Cancer Incidence and Screening"},{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms"},{"id":"https://openalex.org/T10583","display_name":"Cancer-related Molecular Pathways"},{"id":"https://openalex.org/T10755","display_name":"HER2/EGFR in Cancer Research"},{"id":"https://openalex.org/T11067","display_name":"Colorectal Cancer Treatments and Studies"},{"id":"https://openalex.org/T11221","display_name":"Bone health and treatments"},{"id":"https://openalex.org/T11296","display_name":"COVID-19 and healthcare impacts"},{"id":"https://openalex.org/T11355","display_name":"Inflammatory Biomarkers in Disease Prognosis"},{"id":"https://openalex.org/T11469","display_name":"Lymphatic System and Diseases"},{"id":"https://openalex.org/T11491","display_name":"CAR-T cell therapy research"},{"id":"https://openalex.org/T11503","display_name":"Cytokine Signaling Pathways and Interactions"},{"id":"https://openalex.org/T11532","display_name":"Chemokine receptors and signaling"},{"id":"https://openalex.org/T11752","display_name":"Cancer Treatment and Pharmacology"},{"id":"https://openalex.org/T11827","display_name":"Polyomavirus and related diseases"},{"id":"https://openalex.org/T11914","display_name":"PARP inhibition in cancer therapy"},{"id":"https://openalex.org/T12103","display_name":"Cancer Risks and Factors"},{"id":"https://openalex.org/T12172","display_name":"Neutropenia and Cancer Infections"},{"id":"https://openalex.org/T12278","display_name":"Vascular Tumors and Angiosarcomas"},{"id":"https://openalex.org/T12334","display_name":"Lung Cancer Research Studies"},{"id":"https://openalex.org/T12379","display_name":"Cancer Diagnosis and Treatment"},{"id":"https://openalex.org/T12505","display_name":"Peptidase Inhibition and Analysis"},{"id":"https://openalex.org/T12758","display_name":"Saffron Plant Research Studies"},{"id":"https://openalex.org/T13434","display_name":"Cancer Research and Treatment"},{"id":"https://openalex.org/T14326","display_name":"Ear and Head Tumors"},{"id":"https://openalex.org/T14364","display_name":"Clusterin in disease pathology"}],"works_count":81939,"cited_by_count":1499343,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T10685","updated_date":"2026-10-21T03:01:35","created_date":"2024-01-23T15:27:07"}