{"id":"https://openalex.org/T10062","display_name":"MicroRNA in disease regulation","description":"This cluster of papers focuses on the role of microRNAs in gene expression regulation, particularly in the context of cancer development and progression. It covers topics such as microRNA biogenesis, targeting specificity, biomarker potential, and therapeutic applications in cancer treatment.","keywords":[{"id":"https://openalex.org/keywords/microrna","display_name":"microRNA","score":0.3283},{"id":"https://openalex.org/keywords/microrna-target-regulation","display_name":"microRNA target regulation","score":0.6213},{"id":"https://openalex.org/keywords/tumor-suppressor-microrna","display_name":"tumor suppressor microRNA","score":0.8146},{"id":"https://openalex.org/keywords/microrna-target-genes","display_name":"miRNA target genes","score":0.46},{"id":"https://openalex.org/keywords/microrna-expression","display_name":"microRNA expression","score":0.3594},{"id":"https://openalex.org/keywords/microrna-expression-profiling","display_name":"miRNA expression profiling","score":0.4928},{"id":"https://openalex.org/keywords/3-untranslated-region","display_name":"3' untranslated region","score":0.2084},{"id":"https://openalex.org/keywords/circulating-micrornas","display_name":"circulating microRNAs","score":0.544},{"id":"https://openalex.org/keywords/mir-21","display_name":"miR-21","score":0.4007},{"id":"https://openalex.org/keywords/microrna-regulation","display_name":"microRNA regulation","score":0.3514},{"id":"https://openalex.org/keywords/microrna-biogenesis","display_name":"microRNA biogenesis","score":0.5266},{"id":"https://openalex.org/keywords/oncogenic-microrna","display_name":"oncogenic microRNA","score":0.8044},{"id":"https://openalex.org/keywords/microrna-therapy","display_name":"miRNA-based therapy","score":0.595},{"id":"https://openalex.org/keywords/mir-155","display_name":"miR-155","score":0.3161},{"id":"https://openalex.org/keywords/mirna-target-prediction","display_name":"miRNA target prediction","score":0.4852},{"id":"https://openalex.org/keywords/mir-145","display_name":"miR-145","score":0.414},{"id":"https://openalex.org/keywords/microrna-biomarkers","display_name":"microRNA biomarkers","score":0.4524},{"id":"https://openalex.org/keywords/microrna-downregulation","display_name":"microRNA downregulation","score":0.686},{"id":"https://openalex.org/keywords/microrna-signature","display_name":"microRNA signature","score":0.5473},{"id":"https://openalex.org/keywords/mir-34a","display_name":"miR-34a","score":0.403},{"id":"https://openalex.org/keywords/differentially-expressed-mirnas","display_name":"differentially expressed miRNAs","score":0.3616},{"id":"https://openalex.org/keywords/mir-146a","display_name":"miR-146a","score":0.312},{"id":"https://openalex.org/keywords/serum-mirna","display_name":"serum microRNA","score":0.5261},{"id":"https://openalex.org/keywords/mirna-dysregulation","display_name":"microRNA dysregulation","score":0.5205},{"id":"https://openalex.org/keywords/microrna-binding-sites","display_name":"microRNA binding sites","score":0.3859}],"legacy_keywords":"MicroRNA; Gene Expression; Cancer; Regulation; Biomarkers; Biogenesis; Targeting; Therapeutics; Metastasis; Dysregulation","ids":{"openalex":"https://openalex.org/T10062","wikipedia":"https://en.wikipedia.org/wiki/MicroRNA"},"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"},"siblings":[{"id":"https://openalex.org/T10183","display_name":"Breast Cancer Treatment Studies"},{"id":"https://openalex.org/T10433","display_name":"Carcinogens and Genotoxicity Assessment"},{"id":"https://openalex.org/T10515","display_name":"Cancer-related molecular mechanisms research"},{"id":"https://openalex.org/T10620","display_name":"Protease and Inhibitor Mechanisms"},{"id":"https://openalex.org/T10631","display_name":"Cancer, Hypoxia, and Metabolism"},{"id":"https://openalex.org/T11287","display_name":"Cancer Genomics and Diagnostics"},{"id":"https://openalex.org/T11547","display_name":"Sesquiterpenes and Asteraceae Studies"},{"id":"https://openalex.org/T11591","display_name":"NF-\u03baB Signaling Pathways"},{"id":"https://openalex.org/T12465","display_name":"Cancer, Lipids, and Metabolism"},{"id":"https://openalex.org/T13350","display_name":"Myxozoan Parasites in Aquatic Species"},{"id":"https://openalex.org/T13943","display_name":"Beetle Biology and Toxicology Studies"},{"id":"https://openalex.org/T13971","display_name":"Synthesis and Biological Activity"}],"works_count":128102,"cited_by_count":3667283,"works_api_url":"https://api.openalex.org/works?filter=topics.id:T10062","updated_date":"2026-10-20T03:01:21","created_date":"2024-01-23T15:27:05"}