{"id":"https://openalex.org/keywords/pyrogens","display_name":"pyrogens","description":"Substances that induce fever by triggering temperature-regulating responses in the body, including microbial contaminants relevant to injectable medicines.","display_name_alternatives":["pyrogen","pyrogenic substances","fever-inducing substances","fever-producing substances","pyrogenic agents"],"ids":{"openalex":"https://openalex.org/keywords/pyrogens","wikidata":"https://www.wikidata.org/wiki/Q50430141"},"primary_topic":{"id":"https://openalex.org/T11861","display_name":"Thermal Regulation in Medicine","score":0.2976,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11861","display_name":"Thermal Regulation in Medicine","score":0.2976,"subfield":{"id":"https://openalex.org/subfields/2706","display_name":"Critical Care and Intensive Care Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.1269,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11460","display_name":"Analytical Methods in Pharmaceuticals","score":0.0916,"subfield":{"id":"https://openalex.org/subfields/1602","display_name":"Analytical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"works_count":1517,"cited_by_count":24543,"works_api_url":"https://api.openalex.org/works?filter=keywords.id:keywords/pyrogens","updated_date":"2026-10-24T04:06:44","created_date":"2026-09-30T00:00:00"}