{"id":"https://openalex.org/G79914761","display_name":"HIV-1 evolution in the female genital tract and trafficking to the blood","description":"PUBLIC HEALTH RELEVANCE: We have observed that HIV populations may grow in the genital tract because cells with virus appear to proliferate, probably due to infections and traumas (e.g., sexual intercourse, tampons, etc.). If a significant fraction of genital tract HIV is derived from proliferation of infected cells, this phenomenon may present a major obstacle to curing HIV infection; unless novel approaches can be developed to eliminate HIV infection from the body.","funder_award_id":"R01AI091550","funder":{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","doi":"10.13039/100000060"},"funded_outputs":["https://openalex.org/W2059762896","https://openalex.org/W2064416623","https://openalex.org/W2072164469","https://openalex.org/W2154503323","https://openalex.org/W2417835881","https://openalex.org/W2609975224","https://openalex.org/W2801331080","https://openalex.org/W2922618739","https://openalex.org/W3015489715","https://openalex.org/W4401332808","https://openalex.org/W4413491881"],"funded_outputs_count":11,"parent_awards":[],"sub_awards":[{"id":"https://openalex.org/G9001253003","funder":{"display_name":"Seattle Children\u2019s Hospital","id":"https://openalex.org/F4320312116"},"asserted_by":"funder","relationship":"sub_award","display_name":"HIV-1 evolution in the female genital tract and trafficking to the blood (sub-award to UNIVERSITY OF WASHINGTON)"}],"sub_awards_count":1,"amount":null,"currency":"USD","amount_usd":null,"amount_usd_basis":null,"recipients":[],"recipient_countries":[],"recipient_regions":[],"research_scope":{"is_research":true,"basis":"funder_default","tier":1},"funding_type":"research","funder_scheme":"R01","start_date":"2011-01-21","end_date":"2017-12-31","start_year":2011,"end_year":2017,"landing_page_url":"https://reporter.nih.gov/project-details/8081383","doi":null,"provenance":"nih_exporter","lead_investigator":{"given_name":"LISA M","family_name":"FRENKEL","orcid":null,"role_start":null,"affiliation":{"name":"SEATTLE CHILDREN'S HOSPITAL","country":"UNITED STATES","ids":null}},"co_lead_investigator":null,"investigators":null,"works_api_url":"https://api.openalex.org/works?filter=awards.id:G79914761","primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.76,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.76,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"institution_awarded":[{"id":"https://openalex.org/I1295499534","display_name":"Seattle Children's Hospital","ror":"https://ror.org/01njes783","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295499534"]}],"updated_date":"2026-10-29T03:01:01.000Z","created_date":"2026-10-09T19:56:01.000Z"}