{"id":"https://openalex.org/G661982136","display_name":"Development of catalytic transformations that include multiple bond cleavages and formations","description":"In this study, research on catalytic transformations involving multiple bond cleavages and formations was conducted, and more than ten reactions were developed. Spirobiindanones, arylideneindanes, and dihydrophenanthrenes were synthesized by rhodium-catalyzed arylation. Ring-opening coupling reactions of cyclopropenones afforded alkenyl alkynyl ketones and spirocyclic cyclopentanones. Hydrazine derivatives underwent rhodium-catalyzed cyclization reactions to give indoles and phthalazinones. Maleic anhydrides coupled with alkynes and diynes to afford pyrones and benzenes, respectively. Rhodium-catalyzed reaction of pyridylmethylenecyclobutanes gave indanes through a skeletal rearrangement. On the other hand, pyridylmethylenecyclobutenes underwent rhodium-catalyzed intermolecular coupling with alkynes to afford multisubstituted benzenes.","funder_award_id":"25410054","funder":{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","doi":"https://doi.org/10.13039/501100001691"},"funded_outputs":["https://openalex.org/W1560328886","https://openalex.org/W1986601607","https://openalex.org/W2027692386","https://openalex.org/W2051851250","https://openalex.org/W2084988769","https://openalex.org/W2085497245","https://openalex.org/W2111889329","https://openalex.org/W2279486774","https://openalex.org/W2379994136","https://openalex.org/W2461503157","https://openalex.org/W2765545654","https://openalex.org/W2791719301","https://openalex.org/W2911089286","https://openalex.org/W2949132159","https://openalex.org/W2949735790","https://openalex.org/W2951491244","https://openalex.org/W2951533267","https://openalex.org/W2952315667"],"funded_outputs_count":18,"parent_awards":[],"sub_awards":[],"sub_awards_count":0,"amount":5200000.0,"currency":"JPY","amount_usd":55088.94,"amount_usd_basis":"daily_rate","recipients":[],"recipient_countries":[],"recipient_regions":[],"research_scope":{"is_research":true,"basis":"funder_default","tier":1},"funding_type":"research","funder_scheme":"Grant-in-Aid for Scientific Research (C)","start_date":"2013-04-01","end_date":"2016-03-31","start_year":2013,"end_year":2016,"landing_page_url":"https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-25410054/","doi":null,"provenance":"kaken","lead_investigator":{"given_name":"Takanori","family_name":"Matsuda","orcid":null,"role_start":null,"affiliation":{"name":"Tokyo University of Science","country":"Japan","ids":[{"id":"https://nrid.nii.ac.jp/nrid/1000080359778","type":"nrid","asserted_by":"kaken"}]},"author":{"id":"https://openalex.org/A5041041689","display_name":"Takanori Matsuda","orcid":"https://orcid.org/0000-0002-9927-3599"},"institutions":[{"id":"https://openalex.org/I161296585","display_name":"Tokyo University of Science","ror":"https://ror.org/05sj3n476","country_code":"JP","type":"education","lineage":["https://openalex.org/I161296585"]}]},"co_lead_investigator":null,"investigators":null,"works_api_url":"https://api.openalex.org/works?filter=awards.id:G661982136","primary_topic":{"id":"https://openalex.org/T10871","display_name":"Catalytic Alkyne Reactions","score":0.5952,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10871","display_name":"Catalytic Alkyne Reactions","score":0.5952,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10354","display_name":"Catalytic C\u2013H Functionalization Methods","score":0.228,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11611","display_name":"Cyclopropane Reaction Mechanisms","score":0.0908,"subfield":{"id":"https://openalex.org/subfields/1605","display_name":"Organic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/rhodium-catalysis","display_name":"rhodium catalysis","score":0.975},{"id":"https://openalex.org/keywords/dihydrophenanthrene","display_name":"dihydrophenanthrene","score":0.995},{"id":"https://openalex.org/keywords/hydrazine-cyclization","display_name":"hydrazine cyclization","score":0.98},{"id":"https://openalex.org/keywords/indole-synthesis","display_name":"indole synthesis","score":0.885},{"id":"https://openalex.org/keywords/phthalazinone","display_name":"phthalazinone","score":0.94},{"id":"https://openalex.org/keywords/pyrones","display_name":"pyranones","score":0.787},{"id":"https://openalex.org/keywords/skeletal-rearrangement","display_name":"skeletal rearrangement","score":0.889},{"id":"https://openalex.org/keywords/alkyne-coupling","display_name":"alkyne coupling","score":0.639}],"sustainable_development_goals":[],"institution_awarded":[{"id":"https://openalex.org/I161296585","display_name":"Tokyo University of Science","ror":"https://ror.org/05sj3n476","country_code":"JP","type":"education","lineage":["https://openalex.org/I161296585"]}],"updated_date":"2026-11-13T03:01:57.000Z","created_date":"2026-07-13T04:17:19.000Z"}