{"id":"https://openalex.org/G619204443","display_name":"An Instrument to Determine Protein Stability for Biologics Formulations Testing","description":"  This instrument will significantly accelerate the development of protein therapeutics and find a significant market. In addition, it will provide a new way to study protein stability and aggregation, and contribute to the development of a better scientific understanding of these issues. By providing a rapid and cost-effective means to automatically conduct an entire Formulations Study at relevant temperatures (storage and biological), researchers will have the practical opportunity to test more Formulations and to select the Formulation that is optimal for any specific biologic.                ","funder_award_id":"R44GM096751","funder":{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","doi":"https://doi.org/10.13039/100000057"},"funded_outputs":["https://openalex.org/W1980671580","https://openalex.org/W1985034086","https://openalex.org/W2054461066"],"funded_outputs_count":3,"parent_awards":[],"sub_awards":[],"sub_awards_count":0,"amount":null,"currency":"USD","amount_usd":null,"amount_usd_basis":null,"recipients":[],"recipient_countries":[],"recipient_regions":[],"research_scope":{"is_research":true,"basis":"funder_default","tier":1},"funding_type":"research","funder_scheme":"R44","start_date":"2011-01-17","end_date":"2014-03-31","start_year":2011,"end_year":2014,"landing_page_url":"https://reporter.nih.gov/project-details/8307203","doi":null,"provenance":"nih_exporter","lead_investigator":{"given_name":"RICHARD KENNETH","family_name":"BROWN","orcid":null,"role_start":null,"affiliation":{"name":"AVIA BIOSYSTEMS, LLC","country":"UNITED STATES","ids":null},"author":{"id":"https://openalex.org/A5109241144","display_name":"Richard K. J. Brown","orcid":null},"institutions":null},"co_lead_investigator":null,"investigators":null,"works_api_url":"https://api.openalex.org/works?filter=awards.id:G619204443","primary_topic":{"id":"https://openalex.org/T11124","display_name":"Protein purification and stability","score":0.9995,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11124","display_name":"Protein purification and stability","score":0.9995,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12255","display_name":"Biosimilars and Bioanalytical Methods","score":0.0001,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T13539","display_name":"thermodynamics and calorimetric analyses","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1606","display_name":"Physical and Theoretical Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/protein-stability","display_name":"protein stability","score":0.944},{"id":"https://openalex.org/keywords/protein-aggregation","display_name":"protein aggregation","score":0.706},{"id":"https://openalex.org/keywords/therapeutic-proteins","display_name":"therapeutic proteins","score":0.786},{"id":"https://openalex.org/keywords/formulation-development","display_name":"formulation development","score":0.55},{"id":"https://openalex.org/keywords/storage-temperature","display_name":"storage temperature","score":0.538}],"sustainable_development_goals":[],"institution_awarded":[],"updated_date":"2026-11-13T03:01:57.000Z","created_date":"2026-10-09T19:56:01.000Z"}