{"id":"https://openalex.org/G5070052257","display_name":"A new model system to study brain aging and neurodegeneration","description":"PROJECT NARRATIVE Metabolic dysfunction is a common hallmark of aging and neurodegenerative disease. However, the reasons for age-related loss of energy homeostasis remain poorly understood due to limitations in systems to study the molecular mechanisms involved. This study will develop a new model system for studying how the neuroendocrine region of the brain ages.","funder_award_id":"R21AG070527","funder":{"id":"https://openalex.org/F4320337337","display_name":"National Institute on Aging","doi":"10.13039/100000049"},"funded_outputs":["https://openalex.org/W36285248","https://openalex.org/W4283790499","https://openalex.org/W4306790572","https://openalex.org/W4389202278"],"funded_outputs_count":4,"parent_awards":[],"sub_awards":[],"sub_awards_count":0,"amount":null,"currency":"USD","amount_usd":null,"amount_usd_basis":null,"recipients":[],"recipient_countries":[],"recipient_regions":[],"research_scope":{"is_research":true,"basis":"funder_default","tier":1},"funding_type":"research","funder_scheme":"R21","start_date":"2020-09-11","end_date":"2023-08-31","start_year":2020,"end_year":2023,"landing_page_url":"https://reporter.nih.gov/project-details/10109804","doi":null,"provenance":"nih_exporter","lead_investigator":{"given_name":"ASHLEY E","family_name":"WEBB","orcid":null,"role_start":null,"affiliation":{"name":"BROWN UNIVERSITY","country":"UNITED STATES","ids":null}},"co_lead_investigator":null,"investigators":null,"works_api_url":"https://api.openalex.org/works?filter=awards.id:G5070052257","primary_topic":null,"topics":null,"institution_awarded":[{"id":"https://openalex.org/I27804330","display_name":"Brown University","ror":"https://ror.org/05gq02987","country_code":"US","type":"education","lineage":["https://openalex.org/I27804330"]}],"updated_date":"2026-10-16T03:01:01.000Z","created_date":"2026-10-09T19:56:01.000Z"}