{"id":"https://openalex.org/G4150582425","display_name":"MHC-I\u9ad8\u767a\u73fe\u81b5\u764c\u306b\u304a\u3051\u308b\u304c\u3093\u95a2\u9023\u7dda\u7dad\u82bd\u7d30\u80de\u306b\u7740\u76ee\u3057\u305f\u514d\u75ab\u56de\u907f\u6a5f\u69cb\u306e\u89e3\u660e","description":"\u81b5\u764c\u514d\u75ab\u56de\u907f\u6a5f\u69cb\u306b\u304a\u3051\u308bLysosome\u9175\u7d20\u306e\u5f79\u5272\u3092\u8a73\u7d30\u306b\u89e3\u6790\u3057\u3001\u7279\u306bMHC-I\u9ad8\u767a\u73fe\u81b5\u764c\u306b\u304a\u3051\u308b\u9593\u8cea\u304a\u3088\u3073\u304c\u3093\u95a2\u9023\u7dda\u7dad\u82bd\u7d30\u80de\uff08CAF\uff09\u3068\u306e\u95a2\u4fc2\u6027\u306e\u89e3\u660e\u3092\u76ee\u7684\u3068\u3059\u308b\u3002\u81b5\u764c\u306f\u6d3b\u767a\u306a\u30aa\u30fc\u30c8\u30d5\u30a1\u30b8\u30fc\u306b\u3088\u308aMHC-I\u304c\u5206\u89e3\u3055\u308c\u3001\u6297\u539f\u63d0\u793a\u80fd\u304c\u8457\u3057\u304f\u4f4e\u4e0b\u3057\u514d\u75ab\u56de\u907f\u304c\u4fc3\u9032\u3055\u308c\u308b\u3002MHC-I\u9ad8\u767a\u73fe\u72b6\u614b\u306b\u304a\u3044\u3066\u3082CAF\u5897\u751f\u3092\u4e2d\u5fc3\u3068\u3057\u305f\u514d\u75ab\u56de\u907f\u6a5f\u69cb\u306b\u3088\u308a\u9020\u816b\u760d\u6027\u304c\u78ba\u8a8d\u3055\u308c\u305f\u3002\u672c\u7814\u7a76\u3067\u306f\u514d\u75ab\u56de\u907f\u306e\u9375\u3068\u306a\u308bCAF\u5897\u751f\u8a98\u5c0e\u56e0\u5b50\u3092\u7279\u5b9a\u3057\u3001\u6a5f\u80fd\u89e3\u6790\u3092\u884c\u3046\u3002\u7279\u5b9a\u3057\u305f\u56e0\u5b50\u306b\u4ecb\u5165\u3059\u308b\u3053\u3068\u3067\u3001\u65e2\u5b58\u306e\u514d\u75ab\u30c1\u30a7\u30c3\u30af\u30dd\u30a4\u30f3\u30c8\u963b\u5bb3\u5264\u3092\u4f75\u7528\u3057\u305f\u65b0\u305f\u306a\u8907\u5408\u514d\u75ab\u7642\u6cd5\u306e\u5275\u51fa\u3057\u3001\u6709\u52b9\u306a\u514d\u75ab\u7642\u6cd5\u306e\u4e4f\u3057\u3044\u81b5\u81d3\u764c\u306b\u9769\u65b0\u7684\u6cbb\u7642\u6226\u7565\u306e\u78ba\u7acb\u3092\u76ee\u6307\u3059\u3002","funder_award_id":"26K11655","funder":{"id":"https://openalex.org/F4320334764","display_name":"Japan Society for the Promotion of Science","doi":"10.13039/501100001691"},"funded_outputs":["https://openalex.org/W7168150070","https://openalex.org/W7172393205","https://openalex.org/W7223670170"],"funded_outputs_count":3,"parent_awards":[],"sub_awards":[],"sub_awards_count":0,"amount":4550000.0,"currency":"JPY","amount_usd":28739.32,"amount_usd_basis":"daily_rate","recipients":[],"recipient_countries":[],"recipient_regions":[],"research_scope":{"is_research":true,"basis":"funder_default","tier":1},"funding_type":"research","funder_scheme":"Grant-in-Aid for Scientific Research (C)","start_date":"2026-04-01","end_date":"2029-03-31","start_year":2026,"end_year":2029,"landing_page_url":"https://kaken.nii.ac.jp/en/grant/KAKENHI-PROJECT-26K11655/","doi":null,"provenance":"kaken","lead_investigator":{"given_name":"\u7965\u7766","family_name":"\u767d\u4e95","orcid":null,"role_start":null,"affiliation":{"name":"Jikei University School of Medicine","country":"Japan","ids":[{"id":"https://nrid.nii.ac.jp/nrid/1000010785364","type":"nrid","asserted_by":"kaken"}]}},"co_lead_investigator":null,"investigators":null,"works_api_url":"https://api.openalex.org/works?filter=awards.id:G4150582425","primary_topic":null,"topics":null,"institution_awarded":[{"id":"https://openalex.org/I115498069","display_name":"Jikei University School of Medicine","ror":"https://ror.org/039ygjf22","country_code":"JP","type":"education","lineage":["https://openalex.org/I115498069"]}],"updated_date":"2026-10-30T03:00:55.000Z","created_date":"2026-07-13T04:17:19.000Z"}