{"id":"https://openalex.org/G3472906866","display_name":"Identification and Characterization of ALS/FTD Associated Variants Using Whole Genome Sequencing","description":"Project Narrative Amyotrophic lateral sclerosis and frontotemporal dementia (ALS) represent a continuum of disease (ALS/FTD). The etiology of a vast majority of ALS/FTD cases is largely unknown restricted until recently by the high cost of whole genome sequencing. Here, we propose to identify and characterize genetic factors contributing to ALS/FTD using whole genome sequencing data furthering our understanding of disease pathogenesis.","funder_award_id":"R56NS073873","funder":{"id":"https://openalex.org/F4320337359","display_name":"National Institute of Neurological Disorders and Stroke","doi":"10.13039/100000065"},"funded_outputs":["https://openalex.org/W2189443629","https://openalex.org/W2594036075","https://openalex.org/W2930937011","https://openalex.org/W2995141306","https://openalex.org/W3027261607","https://openalex.org/W3107500297","https://openalex.org/W3109484009","https://openalex.org/W3114107609","https://openalex.org/W3118467016","https://openalex.org/W3124559005","https://openalex.org/W3157363683","https://openalex.org/W3162440210","https://openalex.org/W3164197617","https://openalex.org/W3196317695","https://openalex.org/W3213135234","https://openalex.org/W4213246082","https://openalex.org/W4220680064","https://openalex.org/W4221081445","https://openalex.org/W4223651052","https://openalex.org/W4226286160","https://openalex.org/W4228996594","https://openalex.org/W4297264803","https://openalex.org/W4309076667","https://openalex.org/W4312225377","https://openalex.org/W4385860694","https://openalex.org/W4391150978"],"funded_outputs_count":26,"parent_awards":[],"sub_awards":[],"sub_awards_count":0,"amount":null,"currency":"USD","amount_usd":null,"amount_usd_basis":null,"recipients":[],"recipient_countries":[],"recipient_regions":[],"research_scope":{"is_research":true,"basis":"funder_default","tier":1},"funding_type":"research","funder_scheme":"R56","start_date":"2011-07-15","end_date":"2022-08-31","start_year":2011,"end_year":2022,"landing_page_url":"https://reporter.nih.gov/project-details/10216070","doi":null,"provenance":"nih_exporter","lead_investigator":{"given_name":"JOHN E","family_name":"LANDERS","orcid":null,"role_start":null,"affiliation":{"name":"UNIV OF MASSACHUSETTS MED SCH WORCESTER","country":"UNITED STATES","ids":null}},"co_lead_investigator":null,"investigators":null,"works_api_url":"https://api.openalex.org/works?filter=awards.id:G3472906866","primary_topic":{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.9912,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10855","display_name":"Amyotrophic Lateral Sclerosis Research","score":0.9912,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"institution_awarded":[{"id":"https://openalex.org/I166722992","display_name":"University of Massachusetts Chan Medical School","ror":"https://ror.org/0464eyp60","country_code":"US","type":"education","lineage":["https://openalex.org/I166722992"]}],"updated_date":"2026-11-04T03:01:03.000Z","created_date":"2026-10-09T19:56:01.000Z"}
