{"id":"https://openalex.org/G3381654792","display_name":"Harnessing MAIT cells as the next frontier of solid tumour immunotherapy","description":"There is great potential for Mucosal-Associated Invariant T (MAIT) cells to overcome current obstacles impeding conventional T cell immunotherapies, where MAIT cells can be exploited to target solid tumours in a safe, universal manner unrestricted by donor and recipient mismatch. This proposal combines our cutting-edge knowledge and data on MAIT cell biology, T cell engineering, and new nanobody production techniques to generate novel, efficacious MAIT cell therapies in cancer.","funder_award_id":"2030162","funder":{"id":"https://openalex.org/F4320334705","display_name":"National Health and Medical Research Council","doi":"10.13039/501100000925"},"funded_outputs":["https://openalex.org/W7214293960"],"funded_outputs_count":1,"parent_awards":[],"sub_awards":[],"sub_awards_count":0,"amount":970618.6,"currency":"AUD","amount_usd":null,"amount_usd_basis":null,"recipients":[],"recipient_countries":[],"recipient_regions":[],"research_scope":{"is_research":true,"basis":"funder_default","tier":1},"funding_type":"research","funder_scheme":"Ideas Grants - 2023 Ideas Grants","start_date":null,"end_date":null,"start_year":null,"end_year":null,"landing_page_url":null,"doi":null,"provenance":"nhmrc","lead_investigator":{"given_name":"Hui-Fern","family_name":"Koay","orcid":null,"role_start":null,"affiliation":{"name":"University of Melbourne","country":"Australia","ids":null}},"co_lead_investigator":null,"investigators":null,"works_api_url":"https://api.openalex.org/works?filter=awards.id:G3381654792","primary_topic":{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.6931,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11020","display_name":"Immune Cell Function and Interaction","score":0.6931,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"institution_awarded":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]}],"updated_date":"2026-11-05T03:01:09.000Z","created_date":"2026-08-06T15:02:32.000Z"}