{"id":"https://openalex.org/G2854887635","display_name":"Evidence based use of high-efficacy therapies in multiple sclerosis","description":"Multiple sclerosis (MS) is a prominent cause of neurological disability. It is therefore essential to select the best treatment strategy that minimises the risk of irreversible long-term disability. MS is however a variable disease, and not all patients require the same strategy to achieve the best long-term outcome. This research stream aims to personalise treatment decisions by studying in who, how, and when, to use the most potent MS therapies to reduce disability while also minimising risk.","funder_award_id":"2033165","funder":{"id":"https://openalex.org/F4320334705","display_name":"National Health and Medical Research Council","doi":"10.13039/501100000925"},"funded_outputs":["https://openalex.org/W4417520740","https://openalex.org/W7149435012","https://openalex.org/W7161815631","https://openalex.org/W7169840239"],"funded_outputs_count":4,"parent_awards":[],"sub_awards":[],"sub_awards_count":0,"amount":674400.0,"currency":"AUD","amount_usd":null,"amount_usd_basis":null,"recipients":[],"recipient_countries":[],"recipient_regions":[],"research_scope":{"is_research":true,"basis":"funder_default","tier":1},"funding_type":"research","funder_scheme":"Investigator Grants - Emerging Leadership 1 (EL1)","start_date":null,"end_date":null,"start_year":null,"end_year":null,"landing_page_url":null,"doi":null,"provenance":"nhmrc","lead_investigator":{"given_name":"Izanne","family_name":"Roos","orcid":null,"role_start":null,"affiliation":{"name":"University of Melbourne","country":"Australia","ids":null}},"co_lead_investigator":null,"investigators":null,"works_api_url":"https://api.openalex.org/works?filter=awards.id:G2854887635","primary_topic":null,"topics":null,"institution_awarded":[{"id":"https://openalex.org/I165779595","display_name":"The University of Melbourne","ror":"https://ror.org/01ej9dk98","country_code":"AU","type":"education","lineage":["https://openalex.org/I165779595"]}],"updated_date":"2026-10-16T03:01:01.000Z","created_date":"2026-08-06T15:02:32.000Z"}